Studies on phosphorylation (phosphonylation) and bis-phosphorylation (phosphonylation) of tyramine and synthesis of their derivatives

Acta Chimica Sinica ›› 1987, Vol. 45 ›› Issue (7): 696-703. Previous Articles Next Articles

Original Articles

酪胺的磷(膦)酰化反应及其衍生物合成的研究

李玉桂;包容;张宗炳;杨俭美;曹金鸿;蒋晓春

南开大学元素有机化学研究所;北京大学生物系;中国军事医学科学院

发布日期:1987-07-15

Studies on phosphorylation (phosphonylation) and bis-phosphorylation (phosphonylation) of tyramine and synthesis of their derivatives

LI YUGUI;BAO RONG;ZHANG ZONGBING;YANG JIANMIE;CAO JINHONG;JIANG XIAOCHEN

Published:1987-07-15

Abstract

Two series of 32 new organophosphorus compounds with the general formulas RR1P(S)NHCH2CH2C6H4OH-4 and RR1P(S)NHCH2CH2C6H4OP(S)R2R3-4 [R, R2 = alkoxy, Ph; R1, R3 = alkoxy, (un)substituted PhO] were prepared from tyramine. The structures of these compounds were established by elemental anal., IR, NMR, and mass spectrometry. Some show insecticidal activities. The mechanism of preference phosphorylation on N is discussed, as well as the catalytic mechanism of different bases and the difference between phosphorylation and phosphonylation.

Key words: PYRIDINE P, INFRARED SPECTROPHOTOMETRY, ELEMENTAL ANALYSIS, MASS SPECTROGRAPHY, PHOSPHORYL COMPOUNDS, POTASSIUM CARBONATE, PROTON MAGNETIC RESONANCE SPECTROMETRY, THIOPHOSPHATE, DIMETHYLAMINO, NEUROTOXICITY

CLC Number:

O627

Cite this article

LI YUGUI;BAO RONG;ZHANG ZONGBING;YANG JIANMIE;CAO JINHONG;JIANG XIAOCHEN. Studies on phosphorylation (phosphonylation) and bis-phosphorylation (phosphonylation) of tyramine and synthesis of their derivatives[J]. Acta Chimica Sinica, 1987, 45(7): 696-703.

Export EndNote|Reference Manager|ProCite|BibTeX|RefWorks

[1]	Jin, Jikang, Zhang, Fenglian, Wang, Yifeng. Lewis Base-Boryl Radical Enabled Giese Reaction and Barton Decarboxylation of N-Hydroxyphthalimide (NHPI) Esters [J]. Acta Chimica Sinica, 2019, 77(9): 889-894.
[2]	Zhao Desheng, Chen Meisha, Wu Weihui, Guo Ying, Chen Yongxiang, Zhao Yufen, Li Yanmei. Investigation on Small Molecules Targeting Cu(I) Preventing Copper-Mediated Neurotoxicity [J]. Acta Chim. Sinica, 2015, 73(8): 799-807.
[3]	CHEN Ying-Xin, GAO Bao-Jiao, JIANG Gui-Ming, ZHANG Rui-Xia. Constituting Chiral Caves by Using Novel Surface-Molecular Imprinting Technique and Realizating Chiral Separation of Enantiomers of Amino Acid [J]. Acta Chimica Sinica, 2011, 69(14): 1705-1714.
[4]	. Non-isothermal Decomposition Kinetics of Novel Fire Retarded Polyacrylonitrile Copolymer in Air [J]. Acta Chimica Sinica, 2009, 67(18): 2127-2132.
[5]	. Synthesis and Characterization of Temperature- and pH-sensitive Poly[2-(N,N-dimethylamino)ethyl methacrylate-g-N- isopropylacrylamide)] Hydrogels [J]. Acta Chimica Sinica, 2009, 67(16): 1910-1916.
[6]	YANG Jun; CHEN Shuang*. Preparation of Oil-Soluble Cu Nanoparticles by a Two-Phase Method [J]. Acta Chimica Sinica, 2007, 65(20): 2243-2248.
[7]	LI Jian-Guo; LIU Ying; JU Huang-Xian*. A Novel Tetrabase-horseradish Peroxi-dase-H₂O₂ Spectrophotometric System and Its Application to Detection of Enzyme Activity [J]. Acta Chimica Sinica, 2007, 65(15): 1499-1503.
[8]	YAN Yu, YI Min, PENG Jin-Fen, ZHAI Mao-Lin*, HA Hong-Fei. Radiation Grafting of Binary Monomers onto Cotton Cellulose [J]. Acta Chimica Sinica, 2005, 63(15): 1444-1448.
[9]	Li Wen;Liu Hongmin;You Qidong. Application of Dibutyltin Oxide to Deacetylation of Glucosides [J]. Acta Chimica Sinica, 2003, 61(9): 1516-1520.
[10]	Zhang Qizhen;Sheng Xin;Yin Xiaoying;Ji Yiping;Li Guang;Zhao Xiaoguang. Study on a Carbosilane Liquid Crystalline Dendrimer of the First Generation-Containing Twelve 4-Nitroazobenzene Mesogen in Its Periphery [J]. Acta Chimica Sinica, 2003, 61(9): 1478-1483.
[11]	Sun Min;Xin Hao;Zhang Yongan;Wang Kezhi;Jin Linpei;Huang Chunhui. Synthesis, Characterization and Photoelectric Properties of a Novel Carbazole-containing Re(Ⅰ)Complex [J]. Acta Chimica Sinica, 2003, 61(8): 1323-1325.
[12]	Xiao Liren;Gao Feng;Tang Jieyuan;Zhang Wengong. A Study on Coordination Polymer of Dysprosium-electropolyurushiol [J]. Acta Chimica Sinica, 2003, 61(8): 1338-1342.
[13]	Fu Xiaogang;Wu Lizhu;Zhang Liping;Tong Zhenhe. Photosensitized Oxidation of Alkenes with Nafion-Loaded [Ru(bpy)_3] ~(2+) as Photosensitizer [J]. Acta Chimica Sinica, 2003, 61(7): 1036-1039.
[14]	Yu Xianyong;Cai Shuhui;Chen Zhong;Huang Peiqiang. NMR and ESI-MS Studies on the Interactions between Oxodiperoxooxalatovanadate and Organic ligands [J]. Acta Chimica Sinica, 2003, 61(7): 994-999.
[15]	Dou Jianmin;Hu Chunhua;Yao Hiajun$DLi, Yuesheng$ESun Jie;Zheng Peiju. Synthesis and Crystal Structure of Two Closo Twleve-vertex Dinickeladodecaborane Clusters [J]. Acta Chimica Sinica, 2003, 61(7): 1006-1013.

酪胺的磷(膦)酰化反应及其衍生物合成的研究

Studies on phosphorylation (phosphonylation) and bis-phosphorylation (phosphonylation) of tyramine and synthesis of their derivatives

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments