Acta Chimica Sinica ›› 1989, Vol. 47 ›› Issue (5): 506-508. Previous Articles     Next Articles

Original Articles

新生物碱10-羟基脱氧喜树碱

林隆泽;沈积慧;周彤;沈春镒;柯珉珉   

  1. 中国科学院上海药物研究所
  • 发布日期:1989-05-15

New alkaloid: 10-hydroxydeoxycamptothecin

LIN LONGZE;SHEN JIHUI;ZHOU TONG;SHEN CHUNYI;KE MINMIN   

  • Published:1989-05-15

A new alkaloid (I) was isolated from the seeds of Camptotheca acuminata Decne. It was identified as 10-hydroxydeoxycamptothecin with a 20R-configuration by spectral anal. and chem. transformation. It shows a strong cytotoxicity against P388 leukemia cell.

Key words: ALKALOID, HYDROXY GROUP, CIRCULAR DICHROISM, CAMPTOTHECINUM

CLC Number: