Researches on the retention model of protein and relation among the model parameters in the hydrophobic interaction chromatography

Acta Chimica Sinica ›› 1996, Vol. 54 ›› Issue (3): 291-297. Previous Articles Next Articles

Original Articles

蛋白质在疏水作用色谱上的保留模型及其模型参数间关系的研究

郭立安;常建华

第四军医大学唐都医院;西北大学化学系

发布日期:1996-03-15

Researches on the retention model of protein and relation among the model parameters in the hydrophobic interaction chromatography

GUO LIAN;CHANG JIANHUA

Published:1996-03-15

Abstract

In this paper, on the basis of the principles of the preferential hyddration interaction, proceeded from thermodynamics, the retention model of protein on the high performance hydrophobic interaction chromatography (HPHIC or HIC) has been deduced. The relation among the model parameters established has caused the experimental laws observed in the past to have a theoretical bases to follow, and in the light of the above-mentioned models, some important chromatographic characteristics of some proteins on the hydrophobic interaction chromatography have been expounded.

Key words: HIGH SPEED LIQUID CHROMATOGRAPHY, COMPLEXATION, PROTEIN, CHROMATOGRAPHY, THERMODYNAMIC ANALYSIS

CLC Number:

O658
Q51

Cite this article

GUO LIAN;CHANG JIANHUA. Researches on the retention model of protein and relation among the model parameters in the hydrophobic interaction chromatography[J]. Acta Chimica Sinica, 1996, 54(3): 291-297.

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蛋白质在疏水作用色谱上的保留模型及其模型参数间关系的研究

Researches on the retention model of protein and relation among the model parameters in the hydrophobic interaction chromatography

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