A Novel Method for the Synthesis of 2-Arylimidazo(2,1-a) isoquinolines

Acta Chimica Sinica ›› 2002, Vol. 60 ›› Issue (10): 1883-1886. Previous Articles Next Articles

Original Articles

一步法合成2-芳基咪唑并[2，1-a]异喹啉等杂环化合物

王炳祥;孙缓缓;李国栋;王晓蓉;胡宏纹

南京大学.南京(210093);南京大学化学与化工学院,南京(210093)

发布日期:2002-10-15

A Novel Method for the Synthesis of 2-Arylimidazo(2,1-a) isoquinolines

Wang Bingxiang;Sun Yuanyuan;Li Guodong;Wang Xiaorong;Hu Hongwen

State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University,Nanjing(210093)

Published:2002-10-15

Abstract

A one-pot procedure has been developed to prepare the derivatives of 2-arylimidazo (2,1-a)-isoquinolines (2a～2b), 2-arylimidazo (1,2-a) quinolines (4a～4b) and 2-arylimidazo (1,2-a) phthalazines (6a～6c) in moderate yields (51%～62%) by the reaction of isoquinolinium salts, quinolinium salts or phthalazinium salts with ammonium acetate in the presence of tetrakispyridine cobalt(II) dichromate (TPCD).

Key words: GLYOXALINE P, QUINOLINE P, ACETOPHENONE P, ACETAMIDE P, ISOQUINOLINE, PYRIDINE P

CLC Number:

O621

Cite this article

Wang Bingxiang;Sun Yuanyuan;Li Guodong;Wang Xiaorong;Hu Hongwen. A Novel Method for the Synthesis of 2-Arylimidazo(2,1-a) isoquinolines[J]. Acta Chimica Sinica, 2002, 60(10): 1883-1886.

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一步法合成2-芳基咪唑并[2，1-a]异喹啉等杂环化合物

A Novel Method for the Synthesis of 2-Arylimidazo(2,1-a) isoquinolines

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