Bromination of the Alkylbenzene Substrates with N-Bromosuccinimide/H3PO4/Zr(OH)4

Acta Chimica Sinica ›› 2010, Vol. 68 ›› Issue (07): 713-716. Previous Articles Next Articles

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H₃PO₄/Zr(OH)₄高效促进NBS对取代烷基苯的亲电溴代

阮礼波，刘烽，欧文华，毛海舫，潘仙华

(上海应用技术学院香料香精技术与工程学院上海 200235)

投稿日期:2009-06-29 修回日期:2009-09-09 发布日期:2010-04-14
通讯作者: 潘仙华 E-mail:panxh2008@gmail.com

Bromination of the Alkylbenzene Substrates with N-Bromosuccinimide/H₃PO₄/Zr(OH)₄

Ruan Libo Liu Feng Ou Wenhua Mao Haifang Pan Xianhua

(School of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai 200235)

Received:2009-06-29 Revised:2009-09-09 Published:2010-04-14

Abstract

A new method of regioselective monobromination of the alkylbenzene substrates with N-bromosuccinimide promoted by solid acid H₃PO₄/Zr(OH)₄ was developed. The reactions were smoothly carried out in CH₃CN under reflux conditions to give monobromination products in excellent yields (79%～96%). The brominated products of side chain were not observed. Remarkably, the catalyst of the solid acid H₃PO₄/Zr(OH)₄ could be recycled and reused many times.

Key words: bromination, solid acid, substituted alkylbenzene

Cite this article

RUAN Li-Bei, LIU Feng, OU Wen-Hua, MAO Hai-Fang, BO Xian-Hua. Bromination of the Alkylbenzene Substrates with N-Bromosuccinimide/H₃PO₄/Zr(OH)₄[J]. Acta Chimica Sinica, 2010, 68(07): 713-716.

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H₃PO₄/Zr(OH)₄高效促进NBS对取代烷基苯的亲电溴代

Bromination of the Alkylbenzene Substrates with N-Bromosuccinimide/H₃PO₄/Zr(OH)₄

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H3PO4/Zr(OH)4高效促进NBS对取代烷基苯的亲电溴代