Acta Chimica Sinica ›› 2002, Vol. 60 ›› Issue (8): 1536-1538. Previous Articles     Next Articles

Original Articles

用环糊精合成楔筒状主体分子新模型

郝爱友;王金山   

  1. 山东大学化学与化工学院,济南(250100);山东师范大学化学系,济南(250014)
  • 发布日期:2002-08-15

Synthesis of New Cuniform Molecular Host Model Based on β- Cyclodextrin

Hao Aiyou;Wang Jinshan   

  1. School of Chemistry & Chemical Engineering, Shandong University, Jinan(250100);Department of Chemistry, Shandong Normal University, Jinan(250014)
  • Published:2002-08-15

β-Cyclodextrin with the 6-hydroxyls protected by dimethyl-tert- butylsilyl was selectively oxidized by lead tetraacetate. After the silyl groups were removed off by boron fluoride-etherate, mono-2,3- dialdehydro-β-cyclodextrin as a cuniform molecule could be constructed. Mono-2,3-dialdehydro-β-cyclodextrin is more soluble in water than β- cyclodextrin. Mono-2,3-dialdehydo-β-cyclodextrin could be used as the mobile phase additives for effective resolution of DL-adrenaline on silica gel plates.

Key words: CYCLODEXTRIN, MACROCYCLIC COMPOUNDS, EPINEPHRINE, ENANTIOMORPH

CLC Number: