The title compounds (3) have been prepared by 1,4-nucleophilic addition of 2-(1H-1,2,4-triazol-1-yl)-2-propen-1-one with substituted thiophenol or heterocyclic compounds containing mercapto group. Structures of these compounds were characterized by elemental analysis, ~1H NMR and IR spectral data. The results of biological evaluation reveal that most of the compounds possess good fungicidal activities. The study of the relationship of structure and activity indicates that substituent R~1 has significant effect on biological activities of the compounds. Compounds 3 exhibit higher activity against Puccinia recondita in wheat when R~1 is (CH_3)_3C, than when R~1 is Ar, while the substituents on group Ar have little effect on activities.

Key words: PYRRODIAZOLE P, NUCLEOPHILIC REACTION, ADDITION REACTION, BIOLOGICAL ACTIVITY, PROPENONE, THIOPHENOLS