Acta Chimica Sinica ›› 2003, Vol. 61 ›› Issue (2): 291-294. Previous Articles     Next Articles

Original Articles

不同晶型那格列奈的稳定性研究

李钢;徐群为;莫祥银;陈家英;苏国强   

  1. 南京师范大学分析测试中心;江苏省药物研究所
  • 发布日期:2003-02-15

Study on Stability of Nateglinide Polymorphism

Li Gang;Xu Qunwei;Mo Xiangyin;Chen Jiaying;Su Guoqiang   

  1. Testing & Analysis Center, Nanjing Normal University;Jiangsu Institute of Materia Medica
  • Published:2003-02-15

A study has been made on the stability of three forms of nateglinide treated in different conditions, such as temperature, humidity, irradiation and so on. Analysis of the crystal structure was performed by X-ray powder diffraction. Their particle shapes were observed in scan electron microscope. The results show that the stability of S-form of nateglinide is the best among the three forms.

Key words: Nateglinide, DIABETES MELLITUS, XRD, HEAT-TREATMENT

CLC Number: