Reaction of organolithium reagents with fluorinated β-keto- phosphonium salts-a new synthesis of fluoroolefins

Acta Chimica Sinica ›› 1993, Vol. 51 ›› Issue (12): 1209-1213. Previous Articles Next Articles

Original Articles

有机锂试剂和含氟β-酮基磷盐的反应-一种合成含氟烯烃的新方法

沈延昌;邱伟明

中国科学院上海有机化学研究所

发布日期:1993-12-15

Reaction of organolithium reagents with fluorinated β-keto- phosphonium salts-a new synthesis of fluoroolefins

SHEN YANCHANG;QIU WEIMING

Published:1993-12-15

Abstract

A new methodol. for the synthesis of fluoroolefins was described. Organolithium reagents attacked the carbonyl carbon neighboring to the perfluoroalkyl groups in b-ketophosphonium salts, followed by elimination of triphenylphosphine oxide and the tetrasubstituted fluoroolefins were obtained in 42~70% yields (multi-steps) in one-pot reaction. The stereochem. results were discussed.

Key words: ALKENE P, CARBONYL COMPOUNDS, FLUOROHYDROCARBON, NUCLEOPHILIC REACTION, PHOSPHORUS COMPOUNDS, ORGANO LITHIUM COMPOUNDS, YLIDE

CLC Number:

O627

Cite this article

SHEN YANCHANG;QIU WEIMING. Reaction of organolithium reagents with fluorinated β-keto- phosphonium salts-a new synthesis of fluoroolefins[J]. Acta Chimica Sinica, 1993, 51(12): 1209-1213.

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有机锂试剂和含氟β-酮基磷盐的反应-一种合成含氟烯烃的新方法

Reaction of organolithium reagents with fluorinated β-keto- phosphonium salts-a new synthesis of fluoroolefins

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