Acta Chimica Sinica ›› 1989, Vol. 47 ›› Issue (4): 400-403. Previous Articles     Next Articles

Original Articles

赛吲哚霉素糖部分的合成

张军良;蒋湘君;张致平   

  1. 中国医学科学院抗菌素研究所
  • 发布日期:1989-04-15

The synthesis of the sugar moiety of neosindomycin

ZHANG JUNLIANG;JIANG XIANGJUN;ZHANG ZHIPING   

  • Published:1989-04-15

The sugar moiety of neosidomycin, Me (methyl 4-deoxy-b-D-ribo-hexopyranoside)uronate (I) was synthesized from 4-deoxy-D-ribo-hexopyranose through glycosidation, acetonide formation, oxidation, esterification and hydrolysis. The configuration of b-glycoside linkage of the final product was determine from the J1,2 value of its 1H NMR data.

Key words: INDOLE P, CONDENSATION REACTION, ESTERIFICATION, STRONG-ACID CATION-EXCHANGE RESINS, PYRANOSE, GLUCOSE, GLYCOSIDE, METHYL ESTER, URONIC ACID, STREPTOMYCES

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