Studies on interaction between adriamycin and serum albumin as well as effect of ions on the reaction

Acta Chimica Sinica ›› 1997, Vol. 55 ›› Issue (9): 915-920. Previous Articles Next Articles

Original Articles

阿霉素与血清白蛋白的作用及共存离子对反应影响的研究

卢继新;张贵珠;赵鹏;何锡文;史慧明

天津医科大学药学系;南开大学化学系

发布日期:1997-09-15

Studies on interaction between adriamycin and serum albumin as well as effect of ions on the reaction

LU JIXIN;ZHANG GUIZHU;ZHAO PENG;HE XIWEN;SHI HUIMING

Published:1997-09-15

Abstract

The interactions between adriamycin, various trace metal ions and HSA or BSA have been studied using spectrophotometry and fluorescence spectrophotometry. The formation constant of adriamycin to BSA or HSA, the binding ratio and formation constant of adriamycin to ions were obtained. Effect of various ions on the formation constant of adriamycin to HSA was also studied.

Key words: SPECTROPHOTOMETRY, ADRIAMYCINE, FLUOROSPECTROPHOTOMETRY, SERUM PROTEINS, SERUM ALBUMIN

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Cite this article

LU JIXIN;ZHANG GUIZHU;ZHAO PENG;HE XIWEN;SHI HUIMING. Studies on interaction between adriamycin and serum albumin as well as effect of ions on the reaction[J]. Acta Chimica Sinica, 1997, 55(9): 915-920.

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阿霉素与血清白蛋白的作用及共存离子对反应影响的研究

Studies on interaction between adriamycin and serum albumin as well as effect of ions on the reaction

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