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Acta Chimica Sinica ›› 2000, Vol. 58 ›› Issue (10): 1186-1187. Previous Articles Next Articles
Original Articles
杨若林;曾陇梅;苏镜娱;李红
发布日期:
Yang Ruolin;Zeng Longmei;Su Jingyu;Li Hong
Published:
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Four cembrenolides (1~4) were isolated from the soft coral sinularia capillosa collected around Sanya, Hainan Island, China. Compound (1), C~2~0H~3~2O~5, m.p.158~160℃, [α]~D^2^5+42.8°(c 0.05, EtOH) is a new compound. Its structure was elucidated on the basis of spectroscopic data. The relative stereochemistry of 1 was determined to be 1R^*, 4R^*, 5S^*, 12S^*, 13R^* mainly by NOESY and NOE difference spectra. Compound (4), flexibilide, exhibited potent cytotoxicity toward HepA and EAC cell lines.
Key words: SOFT CORAL, SPECTROMETRIC ANALYSIS
CLC Number:
O629
Yang Ruolin;Zeng Longmei;Su Jingyu;Li Hong. A new trihydroxylated cembrenolide diterpene[J]. Acta Chimica Sinica, 2000, 58(10): 1186-1187.
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