The study of separation properties of membrane under electro-driving condition is of an important guiding significance for the application of membrane in microdevices such as microfluidic chip. The electro-driving permeation performance of and Cl^－ of Nylon 6,6 membrane which was prepared by interfacial polymerization was investigated, and effects of electric field, operation time and temperature on the and Cl^－ permeation performance of Nylon 6,6 membrane were studied. Experimental results showed that the permeation percentage of and Cl^－ are high and similar for nylon 6,6 membrane. Ion permeation percentage was increased with electric field strength and operation time, but not changed with temperature. However, FITC labeled glycine and lysine were blocked totally, the molecular weight cutoff is around 500. So in a broader sense, the synthesized nylon 6,6 membrane is one kind of nanofiltration membrane and could be used to separate and concentrate big organic or biological molecules in miniaturized devices.

Key words: Nylon 6,6 membrane, electro-driving, permeation performance, ion permeation percentage