Acta Chimica Sinica ›› 2011, Vol. 69 ›› Issue (24): 3002-3006.DOI: 10.6023/A1101251 Previous Articles     Next Articles

Full Papers

一种基于PVC膜电极的电位式葡萄糖传感器的研制

康平利, 马小燕, 林觅, 郭淑杰, 刘新菲, 王建国*   

  1. (辽宁大学化学院 沈阳 110036)
  • 投稿日期:2011-01-25 修回日期:2011-07-05 发布日期:2011-08-15
  • 通讯作者: 王建国 E-mail:jgwang@lnu.edu.cn
  • 基金资助:

    辽宁省教育厅创新团队基金

Development of a Potentiometric Glucose Biosensor Based on a PVC Membrane Electrode

KANG Ping-Li, MA Xiao-Yan, LIN Mi, GUO Shu-Jie, LIU Xin-Fei, WANG Jian-Guo   

  1. (College of Chemistry, Liaoning University, Shenyang 110036)
  • Received:2011-01-25 Revised:2011-07-05 Published:2011-08-15
  • Contact: WANG Jian-Guo E-mail:jgwang@lnu.edu.cn

Novel polyvinyl chloride (PVC) membrane electrodes containing triheptyl dodecyl ammonium iodide as electroactive materials exhibit excellent potentiometric response to the complex of hydrogen peroxide and hexavalent molybdenum. A potentiometric glucose biosensor was developed based on the PVC film electrode which was employed as a platform to immobilize Glucose oxidase (GOD). Under the optimization experiment conditions, experimental results show that the biosensor responds linearly to glucose in the range from 2×10-4 to 5×10-3 mol/L, the detection limit was 5×10-5 mol/L. In addition, the biosensor exhibits high stability and good selectivity against common interfering species such as ascorbic acid, uric acid and some kinds of amino acids.

Key words: PVC membrane, glucose sensor, hexavalent molybdenum, potentiometric