Study on Syntheses and Anticoagulant Action of Rare Earth Nano-oxides/TDI-CS Hybrid Materials

doi:10.6023/A1103231

Acta Chimica Sinica ›› 2012, Vol. 70 ›› Issue (02): 207-211.DOI: 10.6023/A1103231 Previous Articles Next Articles

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纳米稀土氧化物/硫酸酯化壳聚糖杂化材料的制备及其抗凝血性能研究

高琦宽^a,c, 王坤杰^b, 王喜存^a

a 西北师范大学化学化工学院兰州 730070;
b 兰州理工大学石油化工学院兰州 730050;
c 甘肃省卫生学校兰州 730000

投稿日期:2011-03-23 修回日期:2011-09-14 发布日期:2012-02-25
通讯作者: 王喜存 E-mail:wangluooda@163.com
基金资助:
国家自然科学基金(No.21062017);甘肃省自然科学基金(No.1112RJZA006)和甘肃省高分子材料重点实验室和兰州理工大学博士科研启动资助项目.

Study on Syntheses and Anticoagulant Action of Rare Earth Nano-oxides/TDI-CS Hybrid Materials

Gao Qikuan^a,c, Wang Kunjie^b, Wang Xicun^a

a College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070;
b College of Petrochemical Technology, Lanzhou University of Technology, Lanzhou 730050;
c Gansu Health School, Lanzhou 730000

Received:2011-03-23 Revised:2011-09-14 Published:2012-02-25
Supported by:
Project supported by the National Natural Science Foundation of China (No.21062017) and Natural Science Foundation of Gansu Province (No. 1112RJZA006);Gansu Key Laboratory of Polymer Materials and Lanzhou University of Technology for Ph.D.

Four hybrid materials of RE₂O₃-TDI-CS (TDI=toluene 2,4-diisocyanate, CS=chitosan, RE=Nd, Eu, La, Sc) were prepared by the method of graft. The materials were characterized by infrared spectroscopy, thermogravimetric and scanning electron microscopy, and results showed that the CS was grafted on the surface of rare earth nano-oxides which was modified by TDI. The results of the experiment of anticoagulant and recalcification time showed that the materials have better anticoagulant action than that of RE₂O₃.

Key words: chitosan (CS), rare earth nano-oxide, hybrid material, anticoagulant, recalcification

Cite this article

Gao Qikuan, Wang Kunjie, Wang Xicun. Study on Syntheses and Anticoagulant Action of Rare Earth Nano-oxides/TDI-CS Hybrid Materials[J]. Acta Chimica Sinica, 2012, 70(02): 207-211.

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纳米稀土氧化物/硫酸酯化壳聚糖杂化材料的制备及其抗凝血性能研究

Study on Syntheses and Anticoagulant Action of Rare Earth Nano-oxides/TDI-CS Hybrid Materials

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