Acta Chimica Sinica ›› 1980, Vol. 38 ›› Issue (5): 502-505. Previous Articles     Next Articles

美登素全合成的研究Ⅰ.C1—C8片段的立体选择性合成

潘百川, 张红, 潘纯英, 舒韫, 王照福, 高怡生   

  1. 中国科学院上海药物研究所
  • 投稿日期:1979-08-18 发布日期:2013-06-03

STUDIES ON THE TOTAL SYNTHESES OF MAYTANSINOIDS Ⅰ.STEREOSELECTIVE SYNTHESIS OF C1—C8 FRAGMENT OF MAYTANSINE

PAN BAI-CHUAN, ZHANG HONG, PAN CHUN-YING, SHU YUN, WANG ZHAO-FU, GAO YI-SHENG   

  1. Shanghai Institute of Materia Medica, Academia Sinica, Shanghai
  • Received:1979-08-18 Published:2013-06-03

The antitumor ansa macrolide rnaytansine(1),isolated from Maytenus Ovatus,has attracted immense interests of organic ohemists in many countries.We wish to roport the stereoseleotive syntheses of the C1-C8 fragment with five ohiral centers in natural configuration.