Acta Chimica Sinica ›› 1978, Vol. 36 ›› Issue (3): 193-197. Previous Articles     Next Articles

翼梗五味子的研究——Ⅰ.五味子酚和去氧五味子素的结构

刘嘉森, 黄梅芬, 高耀良   

  1. 中国科学院上海药物研究所
  • 投稿日期:1977-11-16 发布日期:2013-06-03

STUDIES ON THE CONSTITUENTS OF YI-GENG-WU-WEI-ZI(SCHISANDRA HENRYI CLARKE)——Ⅰ.THE STRUCTURES OF SCHISANHENOL AND DEOXYSCHISANDRIN

LIU CHIA-SHEN, HUANG MEI-FEN, KAO YAO-LIANG   

  1. Shanghai Institute of Materia Medica, Academia Sinica
  • Received:1977-11-16 Published:2013-06-03

A new lignan compound, sohisanhenol, has been isolated from the fruits of Yi-(Geng-Wu-Wei-Zi (Schisandra henryi Clarke) (Magnoliaceae),oolleoted from the Xin-yang district of Henan province. Its structure and conformation are established as Ⅰa and Ⅰb respectively, the absolute configurations as biphenyl(R),C7(R) and C8 (S).The conformation and absolute configuration of deoxyschisandrin are the same as that of schisanhenol, the results are shown in Ⅱb and Ⅱa. In studies on mice intoxicated by carbon tetrachloride and preliminary clinical trial of the pationts suffered from chronic virus hepatitis, sohisanhenol has been shown to be ineffective in loworing the serum glntamio-pyruvio transaminase level.