Acta Chimica Sinica ›› 1976, Vol. 34 ›› Issue (4): 283-293. Previous Articles     Next Articles

海南粗榧抗肿瘤有效成分的研究

  

  1. 1. 中国医学科学院药物研究所;
    2. 中国人民解放军第一八七医院
  • 投稿日期:1976-07-09 发布日期:2013-06-03

STUDIES ON THE ANTITUMOR CONSTITUENTS OF CEPHALOTAXUS HAINANENSIS LI.

  1. 1. INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES;
    2. THE 187TH HOSPITAL OF CHINESE PEOPLE'S LIBERATION ARMY
  • Received:1976-07-09 Published:2013-06-03

Eleven alkaloids were isolated from the bark of Cephalotaxus hainanensis Li.Nine of them were identified as deogyharringtonine (Ⅰ),isoharringtonine (Ⅲ), harringtonine (Ⅲ),homoharringtonino (Ⅳ),cephalotaxine (Ⅴ),drupaoine (Ⅵ), desmethyloephalotaginone (Ⅶ),3-epischelhammericine (Ⅷ) and epioephalotaxine (ⅩⅠ),respectively. The struoture of alkaloid Ⅸ, a neiv alkaloid, was postulated on the bases of its spectrometric data as the epimer of "phelline alkaloid 6". Alkaloid X has not yet been characterized due to scarcity of material.