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Acta Chimica Sinica ›› 1976, Vol. 34 ›› Issue (2): 133-142. Previous Articles     Next Articles

创新霉素的全合成

张致平, 许先栋, 黄龙珍, 林吟卿, 李河水, 余志立, 赵春兰   

  1. 中国医学科学院药物研究所
  • 投稿日期:1976-05-12 发布日期:2013-06-03

THE TOTAL SYNTHESIS OF CHUANGHSINMYCIN

CHANG CHI-PING, HSU HSIEN-DONG, HUANG LUNG-CHEN, LIN YIN-CHING, LI HO-SHUI, Yu CHI-LI, CHAO CHUN-LAN   

  1. Institute of Materia Medica, Chinese Academy of Medical Sciences
  • Received:1976-05-12 Published:2013-06-03

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Chuanghsinmycin is a new antibiotic produced by Actinoplctnes jinanensis n.sp.,active against a number of Gram-positive and Gram-negative bacteria.Preliminary clinical results show that it displays certain efficacy in septicemia,as well as urinary and biliary infections.The present paper reports the total synthesis of(±) Chuanghsinmycin.