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Acta Chimica Sinica ›› 1975, Vol. 33 ›› Issue (1): 75-78. Previous Articles Next Articles
李述文, 戴金媛
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LI SHU-WEN, DAI JIN-YUAN
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Deoxyharringtonine (Ⅰ) isolated from Cephalotazzcs plant material is known as an alkaloid with significant inhibitory activity against P-388 leukemia.We now report the synthesis of deoxyharringtonine (Ⅰ) by condensation of a-ketoacid (Ⅳ) with cephalotaxine (Ⅴ) through a Reformatsky reaction.The analogues (Ⅱ,Ⅲ)of deoxyharringtonine (Ⅰ) have been synthesized by the same procedure.
LI SHU-WEN, DAI JIN-YUAN. A STUDY ON THE DEOXYHARRINGTONINE AND ITS ANALOGUES[J]. Acta Chimica Sinica, 1975, 33(1): 75-78.
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