Acta Chimica Sinica ›› 1966, Vol. 32 ›› Issue (3): 276-283. Previous Articles     Next Articles

牛胰岛素A链的合成及其与天然B链组合成结晶胰岛素

汪猷1, 徐杰诚1, 张伟君1, 陈玲玲1, 李鸿绪1, 邢其毅2, 施溥涛2, 陆德培2, 季爱雪2, 李崇熙2, 叶蕴华2, 汤卡罗2   

  1. 1. 中国科学院有机化学研究所;
    2. 北京大学化学系
  • 投稿日期:1966-03-29 发布日期:2013-06-03

SYNTHESIS OF A-CHAIN OF BOVINE INSULIN AND PARTIAL SYNTHESIS OF CRYSTALLINE BOVINE INSULIN FROM SYNTHETIC A-AND NATURAL B-CHAINS

WANG YU1, HSU JE-ZEN1, CHANG WEI-CHUN1, CHENG LING-LING1, LI HONG-SHUEH1, HSING CHI-YI2, SHI PU-TAO2, LOH TEH-PEI2, CHI AI-HSUEH2, LI CHUNG-HSI2, YIEH YUEN-HWA2, TANG KAR-LO2   

  1. 1. Institute of Organic Chemistry, Academia Sinica;
    2. Department of Chemistry, Peking University
  • Received:1966-03-29 Published:2013-06-03

Crystalline bovine insulin has been synthesized from the S-sulphonate derivatives of synthetic A-and natural B-chains of bovine insulin[1], and the A-chain derivative (Ⅰ) has been prepared from synthetic peutide intermediates.