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Acta Chimica Sinica ›› 1962, Vol. 28 ›› Issue (3): 167-172. Previous Articles Next Articles
李钧, 張礼和, 董振环, 王序
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LI CHUN, CHANG LI-HO, TUNG CHEN-HUAN, WANG HSIU(HSIU WANG)
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3-Mercapto-5-hydroxy-1,2,4-triazine and 3-mercapto-5-hydroxy-6-methyl-1,2,4-triazine were alkylated in sodium hydroxide solution with methyl iodide, ethyl iodide, or benzyl chloride to give the corresponding 3-methylmercapto-, 3-ethylmercapto-, or 3-benzyl-mercapto-derivatives.The structures of these compounds were proved by hydrolysis with 10% monochloroacetic acid to the corresponding 3,5-dihydroxy derivatives.3-Methyl-mercapto-5-hydroxy-1,2,4-triazine and 3-benxylmercapto-5-hydroxy-G-methyl-1, 2, 4-triazinc can be synthesized directly and in better yields from S-alkyl-isothiosemicarbazide and the appropriate keto acids.
LI CHUN, CHANG LI-HO, TUNG CHEN-HUAN, WANG HSIU(HSIU WANG). CHEISTRY OF 1,2,4-TRIAZINESⅠ. ALKYLATION REACTION OF 3-MERCAPTO-5-HYDROXY-1,2,4-TRIAZINE DERIVATIVES[J]. Acta Chimica Sinica, 1962, 28(3): 167-172.
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