Acta Chimica Sinica ›› 1956, Vol. 22 ›› Issue (6): 455-459. Previous Articles     Next Articles

3-二烃氨基甲基-苯并氧六圜-4-酮类衍生物的制备

陈俊杰, 孙常晟, 宋鸿锵, 张其楷   

  1. 医学科学院
  • 投稿日期:1956-06-25 发布日期:2013-06-03

PREPARATION OF 3-DIALKYLAMINOMETHYL-7-CHLORO-7-METHOXY-CHROMANONES

CHEN TSIEN-CHIEN, SUN CHANG-SHEG, SOONG HONG-TSIANG, CHANG CHI-CHIEK   

  1. Institute of Medical Sciences
  • Received:1956-06-25 Published:2013-06-03

(1) Six 3-dialkylaminomethyl-7-chloro- and six 3-dialkylaminomethyl-7-methoxy-thromanones, structurely derived from Miracil B, were prepared for the purpose of finding an effective drug in the treatment of Schistosomiasis Japonica. (2) The aqueous solutions of 3-dialkylaminomethyl-chromanones were not stable and yielded precipitate as the result of decomposition. Prom the solutions of 7-chloro-derivatives we isolated the identical product of m.p, 104-105°, while from those of 7-mcthoxy-derivatives we obtained the other identical product of m.p. 66-67°.