For the purpose of synthesis of desdimethylaminoaureomycinic acid(Ⅵ), one of the main degradation products of aureomycin, some close analogs were first prcpared.By means of the method of Bothe and coworkers, we synthesized some compounds of the general formula Ⅸ, which were then subjected to hydrolysis and decarboxylation in ordcr to get the corresponding acid Ⅹ.Through chain-lengthening processes, Ⅹ might be transformed into the desired analogs of Ⅵ.