Acta Chimica Sinica ›› 2005, Vol. 63 ›› Issue (23): 2121-2125. Previous Articles     Next Articles

芳酰胺-吖啶分子钳对中性分子的识别性能II.新型吖啶类分子钳的研究

王健, 张清华, 牟其明, 陈淑华   

  1. 四川大学化学学院, 成都, 610064
  • 投稿日期:2005-04-21 修回日期:2005-08-05 发布日期:2014-02-14
  • 通讯作者: 陈淑华,E-mail:chemchensh@sina.com E-mail:chemchensh@sina.com
  • 作者简介:陈淑华,E-mail:chemchensh@sina.com
  • 基金资助:

    国家自然科学基金(No.20272038)资助项目.

Recognition of Neutral Molecules by Aromatic Amide-Acridine Molecular Tweezers Ⅱ. Studies on Novel Type of Acridine Molecular Tweezers

WANG Jian, ZHANG Qing-Hua, MU Qi-Ming, CHEN Shu-Hua   

  1. The Faculty of Chemistry, Sichuan University, Chengdu 610064
  • Received:2005-04-21 Revised:2005-08-05 Published:2014-02-14

Molecular recognition properties of the novel type of aromatic amide-acridine molecular tweez-ers for phenylamine, phenyldiamine (o-, m-, p-) have been investigated by UV-vis spectroscopic titration in CHCl3 at 25℃. The association constant (Ka) and Gibbs free energy changes (△G°) have been calculated. The results show that all the molecular tweezers (1~7) can form 1:1 inclusion complexes with guest molecules. The main driving forces are multiple hydrogen bonding and van der waals interaction between host and guest molecules. The recognition ability is discussed from the viewpoint of the size/shape-fit and geometrical complementary relationship. Computer-aided study and 1H NMR spectroscopy have been em-ployed to elucidate the binding behavior of these molecular tweezers.

Key words: molecular recognition, aromatic amide-acridine, molecular tweezer, hydrogen bonding, UV spectral titration