Research Progress on Fluorescent Probes in the Second Near-Infrared Window for In Vivo Multiplexed Imaging

doi:10.6023/A24070218

Acta Chimica Sinica ›› 2024, Vol. 82 ›› Issue (10): 1069-1085.DOI: 10.6023/A24070218 Previous Articles Next Articles

Review

近红外二区荧光探针在活体多重成像中的研究进展

蒋励, 陈子晗, 凡勇^*()

复旦大学化学系聚合物工程国家重点实验室上海 200438

投稿日期:2024-07-16 发布日期:2024-09-13

作者简介:

蒋励, 男, 汉族, 2001年出生于浙江温州, 2023年6月毕业于四川大学化学学院, 2023年9月进入复旦大学化学系攻读博士学位, 研究方向为近红外二区多重成像.

陈子晗, 本科毕业于华东师范大学化学与分子工程学院, 2019年9月进入复旦大学化学系攻读博士研究生. 目前已在Angew. Chem. Int. Ed.、TrAC Trend Anal. Chem.等期刊上发表第一作者论文4篇, 研究方向为稀土纳米材料的合成与近红外二区成像、疾病相关标志物的荧光检测方法与体外多靶标诊断.

凡勇, 复旦大学化学系教授, 博士生导师, 国家优秀青年基金获得者. 2009年获得西安交通大学理学学士学位, 2015年获得清华大学物理系理学博士学位, 2015~2018年复旦大学化学系博士后, 2019年1月加入复旦大学化学系, 主要研究领域包括功能性近红外荧光纳米材料、荧光介观材料的设计与合成及其在医学成像、疾病诊断和治疗中的应用.

基金资助:
国家自然科学基金优秀青年基金(22222403); 国家自然科学基金国际(地区)合作与交流项目(22161160320); 国家自然科学基金面上项目(32171377); 上海市基础研究领域重大项目(22JC1400400)

Research Progress on Fluorescent Probes in the Second Near-Infrared Window for In Vivo Multiplexed Imaging

Li Jiang, Zihan Chen, Yong Fan()

State Key Laboratory of Molecular Engineering of Polymers, Department of Chemistry, Fudan University, Shanghai 200433

Received:2024-07-16 Published:2024-09-13
Contact: *E-mail: fan_yong@fudan.edu.cn
Supported by:
National Science Fund for Excellent Young Scholars(22222403); International (Regional) Cooperation and Exchange (ICE) Projects of the National Natural Science Foundation of China (NSFC)(22161160320); National Natural Science Foundation of China(32171377); Key Basic Research Program of Science and Technology Commission of Shanghai Municipality(22JC1400400)

Due to the low absorption and scattering effects as well as near-zero autofluorescence background noise, imaging in the second near-infrared window (NIR-II, 1000~1700 nm) shows deep penetration with a high resolution and signal-to-noise ratio in biological tissues, which makes it one of the promising optical imaging techniques for in vivo study, especially suitable for multiplexed and real-time analysis. In this review, we first discuss the properties and advantages of NIR-II bioimaging, including a division and evaluation of the different NIR-II sub-windows, which analyze the specific properties of each sub-window for various biological applications. Then, we outline the recent design and synthesis of NIR-II fluorescent probes, including rare earth-based nanoparticles, quantum dots, organic molecules, and other NIR-II materials. These materials are critically evaluated for their potential to enhance imaging performance and their specific suitability for different multiplexed imaging scenarios. This review also introduces the equipment used for NIR-II wide-field and microscopic imaging. Additionally, it introduces the two NIR-II multiplexed in vivo imaging modalities: emission multiplexing and excitation multiplexing. Subsequently, multiplexed imaging applications for blood vessel, tumor, lymphatic system, multi-organ, and cellular levels are highlighted, showcasing how these advances allow for more detailed, simultaneous observations of complex biological processes across different scales of biological organization. Such applications demonstrate the growing potential of NIR-II multiplexed imaging in providing new insights into disease mechanisms and in aiding the development of more targeted therapeutic strategies. Finally, dynamic multiplexed NIR-II imaging offers significant potential for advancing biomedical research and clinical applications by enabling deep-tissue, high-resolution imaging of multiple biological targets. However, current limitations in the availability and applicability of probes necessitate further development of efficient, long-wavelength probes and addressing challenges related to biological safety and clinical translation. As the technology advances, NIR-II imaging is expected to achieve breakthroughs in real-time dynamic multiplexed imaging and functional biosensing, paving the way for its integration into clinical applications.

Key words: second near-infrared window, fluorescent probes, multiplexed imaging, in vivo analysis

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Li Jiang, Zihan Chen, Yong Fan. Research Progress on Fluorescent Probes in the Second Near-Infrared Window for In Vivo Multiplexed Imaging[J]. Acta Chimica Sinica, 2024, 82(10): 1069-1085.

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Fig. & Tab. 7

Figure 1. Light attenuation in biological tissues: (a) light-tissue interactions[35]; (b) autofluorescence spectra of different tissues at 808 nm laser excitation[35]; (c) reduced scattering coefficients (μs') of different biological tissues and intralipid tissue from 400 to 2000 nm; (d) absorption spectra of water from 400 nm to 2300 nm; (e) imaging results of mouse vasculature across different NIR-II regions[12]; (f) the simulation results of NIR biological tissue imaging via the Monte Carlo method[36]

Figure 2. NIR-II fluorescence probes: (a) NIR luminescence spectra and the energy levels of various lanthanide ions including Sm3+, Yb3+, Nd3+, Ho3+, Tm3+, Pr3+, Dy3+, and Er3+ in crystals hosts[72]; (b) metal-macrocycles complexes[66]; (c) emission spectra of Ag2Te quantum dots of different sizes[80]; (d) the mechanism of AIE through restriction of intramolecular motion at a morphological level[81]; (e) example structures of the NIR-II molecular fluorophores polymethine, D-A-D dyes and Silicon-RosIndolizine[64,82???-86]; (f) SWCNTs modified by π-π stacking[87]; (g) Au25 nanoclusters[88]; (h) self-limited assembly of CISe nanotubes[89]

Figure 3. NIR-II imaging equipment: (a) wide-field NIR-II fluorescence imaging[59]; (b) lifetime-resolved imaging[30]; (c) raster-scan confocal NIR-II fluorescence imaging[111]; (d) the custom-built NIR-II dual-channel microscopy system[118]; (e) NIR-II light-sheet microscopy[111]

Figure 4. NIR-II multiplexed in vivo imaging modalities: (a) emission multiplexing; (b) excitation multiplexing

Figure 5. Multiplexed imaging of vascular, tumor, and lymph systems: (a) NIR-II imaging of a brain tumor, arteries and veins[98]; (b) dual-channel NIR-IIb imaging of a mouse bearing a CT-26 tumor at 24 h post intravenous injection of ErNPs-aPDL1 and PbS QDs-aCD8[112]; (c) dual-channel bioluminescence imaging of lymph system with NIR-I-BPs and NIR-II-BPs[123]; (d) utilizing multiplexed lifetime imaging for precise diagnosis and treatment of breast cancer[30]; (e) utilization of NIR-II fluorescence imaging during glioma surgery; (f) utilization of NIR-II fluorescence imaging during cervical cancer surgery[128]

Figure 6. Multiplexed imaging of organs: (a) multiplexed lifetime imaging of organs in vivo and in vitro[124]; (b) dual-channel in vivo PL imaging of organs in a living mouse[122]; (c) dynamic multiplexed imaging of blood vessels and small intestine[70]

Figure 7. Multiplexed imaging of cell: (a) mice received CT1530-labelled cells and Cy7.5-labelled phospholipid micelles through intracardiac injection, followed by through-skull intravital microscopy[66] ; (b) representative images of the CT1530-labelled 143B cells and the Cy7.5-labelled vessels with their overlay image[66]; (c) three-dimensional volumetric NIR-II SIM images of tumor tissue ex vivo[13]; (d) real-time imaging of neutrophils within blood vessels[12]

References 130

[1]	Fan, Y.; Wang, S.; Zhang, F. Angew. Chem. Int. Ed. 2019, 58 13208.
[2]	Shimomura, O.; Johnson, F. H.; Saiga, Y. J. Cell. Physiol. 1962, 59 223.
[3]	Hell, S. W.; Wichmann, J. Opt. Lett. 1994, 19 780. doi: 10.1364/ol.19.000780 pmid: 19844443
[4]	Reinhardt, S. C. M.; Masullo, L. A.; Baudrexel, I.; Steen, P. R.; Kowalewski, R.; Eklund, A. S.; Strauss, S.; Unterauer, E. M.; Schlichthaerle, T.; Strauss, M. T.; Klein, C.; Jungmann, R. Nature 2023, 617 711.
[5]	Irkle, A.; Vesey, A. T.; Lewis, D. Y.; Skepper, J. N.; Bird, J. L. E.; Dweck, M. R.; Joshi, F. R.; Gallagher, F. A.; Warburton, E. A.; Bennett, M. R.; Brindle, K. M.; Newby, D. E.; Rudd, J. H.; Davenport, A. P. Nat. Commun. 2015, 6 7495.
[6]	Helms, G.; Dathe, H.; Kallenberg, K.; Dechent, P. Magn. Reson. Med. 2008, 60 1396.
[7]	Clough, T. J.; Jiang, L.; Wong, K.-L.; Long, N. J. Nat. Commun. 2019, 10 1420.
[8]	Jathoul, A. P.; Laufer, J.; Ogunlade, O.; Treeby, B.; Cox, B.; Zhang, E.; Johnson, P.; Pizzey, A. R.; Philip, B.; Marafioti, T.; Lythgoe, M. F.; Pedley, R. B.; Pule, M. A.; Beard, P. Nat. Photonics 2015, 9 239.
[9]	Pu, K.; Shuhendler, A. J.; Jokerst, J. V.; Mei, J.; Gambhir, S. S.; Bao, Z.; Rao, J. Nat. Nanotechnol. 2014, 9 233.
[10]	Pratt, E. C.; Skubal, M.; Mc Larney, B.; Causa-Andrieu, P.; Das, S.; Sawan, P.; Araji, A.; Riedl, C.; Vyas, K.; Tuch, D.; Grimm, J. Nat. Biomed. Eng. 2022, 6 559.
[11]	Hu, L.; Dong, C.; Wang, Z.; He, S.; Yang, Y.; Zi, M.; Li, H.; Zhang, Y.; Chen, C.; Zheng, R.; Jia, S.; Liu, J.; Zhang, X.; He, Y. Aging Cell 2023, 22, e13896.
[12]	Yang, Y.; Chen, Y.; Pei, P.; Fan, Y.; Wang, S.; Zhang, H.; Zhao, D.; Qian, B.-Z.; Zhang, F. Nat. Nanotechnol. 2023, 18 1195.
[13]	Ren, F.; Wang, F.; Baghdasaryan, A.; Li, Y.; Liu, H.; Hsu, R.; Wang, C.; Li, J.; Zhong, Y.; Salazar, F.; Xu, C.; Jiang, Y.; Ma, Z.; Zhu, G.; Zhao, X.; Wong, K. K.; Willis, R.; Christopher Garcia, K.; Wu, A.; Mellins, E.; Dai, H. Nat. Biomed. Eng. 2023, 726.
[14]	Li, C.; Wang, Q. ACS Nano 2018, 12 9654.
[15]	Ntziachristos, V. Nat. Methods 2010, 7 603. doi: 10.1038/nmeth.1483 pmid: 20676081
[16]	Voelker, R. JAMA 2022, 327 27.
[17]	Zhang, P.; Wu, Q.; Yang, J.; Hou, M.; Zheng, B.; Xu, J.; Chai, Y.; Xiong, L.; Zhang, C. Acta Biomater. 2022, 146 450.
[18]	Ding, S.; Lu, L.; Fan, Y.; Zhang, F. J. Rare Earths 2020, 38 451.
[19]	Frangioni, J. V. Curr. Opin. Chem. Biol. 2003, 7 626. doi: 10.1016/j.cbpa.2003.08.007 pmid: 14580568
[20]	Lai, Y.; Dang, Y.; Sun, Q.; Pan, J.; Yu, H.; Zhang, W.; Xu, Z. Chem. Sci. 2022, 13 12511. doi: 10.1039/d2sc05242c pmid: 36349272
[21]	Feng, Z.; Bai, S.; Qi, J.; Sun, C.; Zhang, Y.; Yu, X.; Ni, H.; Wu, D.; Fan, X.; Xue, D.; Liu, S.; Chen, M.; Gong, J.; Wei, P.; He, M.; Lam, J. W. Y.; Li, X.; Tang, B. Z.; Gao, L.; Qian, J. Adv. Mater. 2021, 33 2008123.
[22]	Yu, W. Q.; Liu, R.; Zhou, Y.; Gao, H. L. ACS Cent. Sci. 2020, 6 100.
[23]	Zhang, Z.; Du, Y.; Shi, X.; Wang, K.; Qu, Q.; Liang, Q.; Ma, X.; He, K.; Chi, C.; Tang, J.; Liu, B.; Ji, J.; Wang, J.; Dong, J.; Hu, Z.; Tian, J. Nat. Rev. Clin. Oncol. 2024, 21 449. doi: 10.1038/s41571-024-00892-0 pmid: 38693335
[24]	Peloso, A.; Franchi, E.; Canepa, M. C.; Barbieri, L.; Briani, L.; Ferrario, J.; Bianco, C.; Quaretti, P.; Brugnatelli, S.; Dionigi, P.; Maestri, M. HPB 2013, 15 928.
[25]	Cousins, A.; Thompson, S. K.; Wedding, A. B.; Thierry, B. Biotechnol. Adv. 2014, 32 269. doi: 10.1016/j.biotechadv.2013.10.011 pmid: 24189095
[26]	Hong, G.; Antaris, A. L.; Dai, H. Nat. Biomed. Eng. 2017, 1 0010.
[27]	Lifante, J.; Shen, Y.; Ximendes, E.; Martín Rodríguez, E.; Ortgies, D. H. J. Appl. Phys. 2020, 128 171101.
[28]	Huang, S.; Heikal, A. A.; Webb, W. W. Biophys. J. 2002, 82 2811.
[29]	Becker, W. J. Microsc. 2012, 247 119.
[30]	Fan, Y.; Wang, P.; Lu, Y.; Wang, R.; Zhou, L.; Zheng, X.; Li, X.; Piper, J. A.; Zhang, F. Nat. Nanotechnol. 2018, 13 941.
[31]	Jacques, S. L. Phys. Med. Biol. 2013, 58, R37.
[32]	Horton, N. G.; Wang, K.; Kobat, D.; Clark, C. G.; Wise, F. W.; Schaffer, C. B.; Xu, C. Nat. Photonics 2013, 7 205.
[33]	Wang, F.; Ren, F.; Ma, Z.; Qu, L.; Gourgues, R.; Xu, C.; Baghdasaryan, A.; Li, J.; Zadeh, I. E.; Los, J. W. N.; Fognini, A.; Qin-Dregely, J.; Dai, H. Nat. Nanotechnol. 2022, 17 653.
[34]	Pansare, V. J.; Hejazi, S.; Faenza, W. J.; Prud’homme, R. K. Chem. Mater. 2012, 24 812. pmid: 22919122
[35]	Chen, Y.; Wang, S.; Zhang, F. Nat. Rev. Bioeng. 2023, 1 60.
[36]	Feng, Z.; Tang, T.; Wu, T.; Yu, X.; Zhang, Y.; Wang, M.; Zheng, J.; Ying, Y.; Chen, S.; Zhou, J.; Fan, X.; Zhang, D.; Li, S.; Zhang, M.; Qian, J. Light Sci. Appl. 2021, 10 197.
[37]	Carr, J. A.; Aellen, M.; Franke, D.; So, P. T. C.; Bruns, O. T.; Bawendi, M. G. Proc. Natl. Acad. Sci. 2018, 115 9080.
[38]	Feng, Z.; Li, Y.; Chen, S.; Li, J.; Wu, T.; Ying, Y.; Zheng, J.; Zhang, Y.; Zhang, J.; Fan, X.; Yu, X.; Zhang, D.; Tang, B. Z.; Qian, J. Nat. Commun. 2023, 14 5017. doi: 10.1038/s41467-023-40728-6 pmid: 37596326
[39]	Koman, V. B.; Bakh, N. A.; Jin, X.; Nguyen, F. T.; Son, M.; Kozawa, D.; Lee, M. A.; Bisker, G.; Dong, J.; Strano, M. S. Nat. Nanotechnol. 2022, 17 643.
[40]	Ming, J.; Chen, Y.; Miao, H.; Fan, Y.; Wang, S.; Chen, Z.; Guo, Z.; Guo, Z.; Qi, L.; Wang, X.; Yun, B.; Pei, P.; He, H.; Zhang, H.; Tang, Y.; Zhao, D.; Wong, G. K.-L.; Bünzli, J.-C. G.; Zhang, F. Nat. Photonics 2024, DOI: 10.1038/s41566-024-01517-9.
[41]	Mei, M.; Wu, B.; Wang, S.; Zhang, F. Curr. Opin. Chem. Biol. 2024, 80 102469.
[42]	Wang, F. F.; Ma, Z. R.; Zhong, Y. T.; Salazar, F.; Xu, C.; Ren, F. Q.; Qu, L. Q.; Wu, A. M.; Dai, H. J. Proc. Natl. Acad. Sci. 2021, 118, e2023888118.
[43]	Ma, Z. R.; Wang, F. F.; Zhong, Y. T.; Salazar, F.; Li, J. C.; Zhang, M. X.; Ren, F. Q.; Wu, A. N. M.; Dai, H. J. Angew. Chem. Int. Ed. 2020, 59 20552.
[44]	Zhu, X.; Zhang, H.; Zhang, F. Acc. Mater. Res. 2023, 4 536.
[45]	Zhao, M.; Sik, A.; Zhang, H.; Zhang, F. Adv. Opt. Mater. 2023, 11 2202039.
[46]	Ma, Z. R.; Wan, H.; Wang, W. Z.; Zhang, X. D.; Uno, T.; Yang, Q. L.; Yue, J. Y.; Gao, H. P.; Zhong, Y. T.; Tian, Y.; Sun, Q. C.; Liang, Y. Y.; Dai, H. J. Nano Res. 2019, 12 273.
[47]	Zhu, X.; Wang, X.; Zhang, H.; Zhang, F. Angew. Chem. Int. Ed. 2022, 61, e202209378.
[48]	Wan, H.; Ma, H. L.; Zhu, S. J.; Wang, F. F.; Tian, Y.; Ma, R.; Yang, Q. L.; Hu, Z. B.; Zhu, T.; Wang, W. Z.; Ma, Z. R.; Zhang, M. X.; Zhong, Y. T.; Sun, H. T.; Liang, Y. Y.; Dai, H. J. Adv. Funct. Mater. 2018, 28 1804956.
[49]	Zhong, Y. T.; Ma, Z. R.; Zhu, S. J.; Yue, J. Y.; Zhang, M. X.; Antaris, A. L.; Yuan, J.; Cui, R.; Wan, H.; Zhou, Y.; Wang, W. Z.; Huang, N. F.; Luo, J.; Hu, Z. Y.; Dai, H. J. Nat. Commun. 2017, 8 737.
[50]	Antaris, A. L.; Chen, H.; Cheng, K.; Sun, Y.; Hong, G. S.; Qu, C. R.; Diao, S.; Deng, Z. X.; Hu, X. M.; Zhang, B.; Zhang, X. D.; Yaghi, O. K.; Alamparambil, Z. R.; Hong, X. C.; Cheng, Z.; Dai, H. J. Nat. Mater. 2016, 15 235.
[51]	Diao, S.; Blackburn, J. L.; Hong, G. S.; Antaris, A. L.; Chang, J. L.; Wu, J. Z.; Zhang, B.; Cheng, K.; Kuo, C. J.; Dai, H. J. Angew. Chem. Int. Ed. 2015, 54 14758.
[52]	Hong, G. S.; Robinson, J. T.; Zhang, Y. J.; Diao, S.; Antaris, A. L.; Wang, Q. B.; Dai, H. J. Angew. Chem. Int. Ed. 2012, 51 9818.
[53]	Hong, G. S.; Lee, J. C.; Robinson, J. T.; Raaz, U.; Xie, L. M.; Huang, N. F.; Cooke, J. P.; Dai, H. J. Nat. Med. 2012, 18 1841.
[54]	Welsher, K.; Sherlock, S. P.; Dai, H. J. Proc. Natl. Acad. Sci. 2011, 108 8943.
[55]	Liu, Z.; Tabakman, S.; Welsher, K.; Dai, H. J. Nano Res. 2009, 2 85.
[56]	Xiong, L.; Fan, Y.; Zhang, F. Acta Chim. Sinica 2019, 77 1239 (in Chinese). doi: 10.6023/A19080305
	(熊麟, 凡勇, 张凡, 化学学报, 2019, 77 1239.) doi: 10.6023/A19080305
[57]	Welsher, K.; Liu, Z.; Sherlock, S. P.; Robinson, J. T.; Chen, Z.; Daranciang, D.; Dai, H. J. Nat. Nanotechnol. 2009, 4 773. doi: 10.1038/nnano.2009.294 pmid: 19893526
[58]	Diao, S.; Hong, G. S.; Antaris, A. L.; Blackburn, J. L.; Cheng, K.; Cheng, Z.; Dai, H. J. Nano Res. 2015, 8 3027.
[59]	Wang, F.; Zhong, Y.; Bruns, O.; Liang, Y.; Dai, H. Nat. Photonics 2024, 18 535.
[60]	Chen, G.; Tian, F.; Zhang, Y.; Zhang, Y.; Li, C.; Wang, Q. Adv. Funct. Mater. 2014, 24 2481.
[61]	Naczynski, D. J.; Tan, M. C.; Zevon, M.; Wall, B.; Kohl, J.; Kulesa, A.; Chen, S.; Roth, C. M.; Riman, R. E.; Moghe, P. V. Nat. Commun. 2013, 4 2199. doi: 10.1038/ncomms3199 pmid: 23873342
[62]	Ren, F.; Ding, L.; Liu, H.; Huang, Q.; Zhang, H.; Zhang, L.; Zeng, J.; Sun, Q.; Li, Z.; Gao, M. Biomaterials 2018, 175 30.
[63]	Wang, R.; Li, X.; Zhou, L.; Zhang, F. Angew. Chem. Int. Ed. 2014, 53 12086. doi: 10.1002/anie.201407420 pmid: 25196421
[64]	Li, B.; Zhao, M.; Zhang, F. ACS Mater. Lett. 2020, 2 905.
[65]	Yu, G. T.; Luo, M. Y.; Li, H.; Chen, S.; Huang, B.; Sun, Z. J.; Cui, R.; Zhang, M. ACS Nano 2019, 13 12830.
[66]	Wang, T.; Wang, S.; Liu, Z.; He, Z.; Yu, P.; Zhao, M.; Zhang, H.; Lu, L.; Wang, Z.; Wang, Z.; Zhang, W.; Fan, Y.; Sun, C.; Zhao, D.; Liu, W.; Bünzli, J.-C. G.; Zhang, F. Nat. Mater. 2021, 20 1571.
[67]	Qi, J.; Sun, C.; Zebibula, A.; Zhang, H.; Kwok, R. T. K.; Zhao, X.; Xi, W.; Lam, J. W. Y.; Qian, J.; Tang, B. Z. Adv. Mater. 2018, 30, e1706856.
[68]	He, A.; Li, X.; Dai, Z.; Li, Q.; Zhang, Y.; Ding, M.; Wen, Z.-F.; Mou, Y.; Dong, H. J. Nanobiotechnol. 2023, 21 236.
[69]	Chang, Y. L.; Chen, H. R.; Xie, X. Y.; Wan, Y.; Li, Q. Q.; Wu, F. X.; Yang, R.; Wang, W.; Kong, X. G. Nat. Commun. 2023, 14 1079.
[70]	Chen, Z. H.; Wang, X.; Yang, M.; Ming, J.; Yun, B.; Zhang, L.; Wang, X.; Yu, P.; Xu, J.; Zhang, H.; Zhang, F. Angew. Chem. Int. Ed. 2023, 62, e202311883.
[71]	Tong, S.; Zhong, J.; Chen, X.; Deng, X.; Huang, J.; Zhang, Y.; Qin, M.; Li, Z.; Cheng, H.; Zhang, W.; Zheng, L.; Xie, W.; Qiu, P.; Wang, K. ACS Nano 2023, 17 3686.
[72]	Yang, Y.; Jiang, Q.; Zhang, F. Chem. Rev. 2024, 124 554. doi: 10.1021/acs.chemrev.3c00506 pmid: 37991799
[73]	Yang, M.; Gong, H.; Yang, D.; Feng, L.; Gai, S.; Zhang, F.; Ding, H.; He, F.; Yang, P. Chin. Chem. Lett. 2024, 35 108468.
[74]	Ren, F.; Jiang, Z.; Han, M.; Zhang, H.; Yun, B.; Zhu, H.; Li, Z. VIEW 2021, 2 20200128.
[75]	Fan, Y.; Zhang, F. Adv. Opt. Mater. 2019, 7 1801417.
[76]	Fan, Y.; Liu, L.; Zhang, F. Nano Today 2019, 25 68.
[77]	Wu, Z.; Ke, J.; Liu, Y.; Sun, P.; Hong, M. Acta Chim. Sinica 2022, 80 542 (in Chinese).
	(吴志芬, 柯建熙, 刘永升, 孙蓬明, 洪茂椿, 化学学报, 2022, 80 542.) doi: 10.6023/A21120571
[78]	Nannuri, S. H.; Kulkarni, S. D.; , K, S. C.; Chidangil, S.; George, S. D. RSC Adv. 2019, 9 9364.
[79]	Jin, G. Q.; Guo, L. J.; Zhang, J.; Gao, S.; Zhang, J. L. Top. Curr. Chem. 2022, 380 31.
[80]	Liu, Z. Y.; Liu, A. A.; Fu, H.; Cheng, Q. Y.; Zhang, M. Y.; Pan, M. M.; Liu, L. P.; Luo, M. Y.; Tang, B.; Zhao, W.; Kong, J.; Shao, X.; Pang, D. W. J. Am. Chem. Soc. 2021, 143 12867.
[81]	Li, Y.; Cai, Z.; Liu, S.; Zhang, H.; Wong, S. T. H.; Lam, J. W. Y.; Kwok, R. T. K.; Qian, J.; Tang, B. Z. Nat. Commun. 2020, 11 1255.
[82]	Zhu, X.; Liu, C.; Hu, Z.; Liu, H.; Wang, J.; Wang, Y.; Wang, X.; Ma, R.; Zhang, X.; Sun, H.; Liang, Y. Nano Res. 2020, 13 2570.
[83]	Sun, C.; Li, B.; Zhao, M.; Wang, S.; Lei, Z.; Lu, L.; Zhang, H.; Feng, L.; Dou, C.; Yin, D.; Xu, H.; Cheng, Y.; Zhang, F. J. Am. Chem. Soc. 2019, 141 19221.
[84]	Cosco, E. D.; Spearman, A. L.; Ramakrishnan, S.; Lingg, J. G. P.; Saccomano, M.; Pengshung, M.; Arús, B. A.; Wong, K. C. Y.; Glasl, S.; Ntziachristos, V.; Warmer, M.; McLaughlin, R. R.; Bruns, O. T.; Sletten, E. M. Nat. Chem. 2020, 12 1123.
[85]	Zhu, S.; Herraiz, S.; Yue, J.; Zhang, M.; Wan, H.; Yang, Q.; Ma, Z.; Wang, Y.; He, J.; Antaris, A. L.; Zhong, Y.; Diao, S.; Feng, Y.; Zhou, Y.; Yu, K.; Hong, G.; Liang, Y.; Hsueh, A. J.; Dai, H. Adv. Mater. 2018, 30, e1705799.
[86]	Meador, W. E.; Lin, E. Y.; Lim, I.; Friedman, H. C.; Ndaleh, D.; Shaik, A. K.; Hammer, N. I.; Yang, B.; Caram, J. R.; Sletten, E. M.; Delcamp, J. H. Nat. Chem. 2024, 16 970.
[87]	Cherukuri, P.; Bachilo, S. M.; Litovsky, S. H.; Weisman, R. B. J. Am. Chem. Soc. 2004, 126 15638. pmid: 15571374
[88]	Baghdasaryan, A.; Wang, F.; Ren, F.; Ma, Z.; Li, J.; Zhou, X.; Grigoryan, L.; Xu, C.; Dai, H. Nat. Commun. 2022, 13 5613. doi: 10.1038/s41467-022-33341-6 pmid: 36153336
[89]	Chang, B.; Li, D.; Ren, Y.; Qu, C.; Shi, X.; Liu, R.; Liu, H.; Tian, J.; Hu, Z.; Sun, T.; Cheng, Z. Nat. Biomed. Eng. 2022, 6 629.
[90]	Wegner, K. D.; Hildebrandt, N. Chem. Soc. Rev. 2015, 44 4792. doi: 10.1039/c4cs00532e pmid: 25777768
[91]	Xie, R.; Rutherford, M.; Peng, X. J. Am. Chem. Soc. 2009, 131 5691.
[92]	Huang, B.; Tang, T.; Liu, F.; Chen, S.-H.; Zhang, Z.-L.; Zhang, M.; Cui, R. Chin. Chem. Lett. 2024, 109694.
[93]	Shen, S.; Wang, Q. Chem. Mater. 2013, 25 1166.
[94]	Zebibula, A.; Alifu, N.; Xia, L.; Sun, C.; Yu, X.; Xue, D.; Liu, L.; Li, G.; Qian, J. Adv. Funct. Mater. 2018, 28 1703451.
[95]	Zhang, M.; Yue, J.; Cui, R.; Ma, Z.; Wan, H.; Wang, F.; Zhu, S.; Zhou, Y.; Kuang, Y.; Zhong, Y.; Pang, D.-W.; Dai, H. Proc. Natl. Acad. Sci. 2018, 115 6590.
[96]	Zheng, W.; Gao, G.; Deng, H.; Sun, T. Acta Chim. Sinica 2023, 81 763 (in Chinese).
	(郑文山, 高冠斌, 邓浩, 孙涛垒, 化学学报, 2023, 81 763.) doi: 10.6023/A23040128
[97]	Jeong, S.; Jung, Y.; Bok, S.; Ryu, Y. M.; Lee, S.; Kim, Y. E.; Song, J.; Kim, M.; Kim, S. Y.; Ahn, G. O.; Kim, S. Adv. Healthcare Mater. 2018, 7, e1800695.
[98]	Bruns, O. T.; Bischof, T. S.; Harris, D. K.; Franke, D.; Shi, Y.; Riedemann, L.; Bartelt, A.; Jaworski, F. B.; Carr, J. A.; Rowlands, C. J.; Wilson, M. W. B.; Chen, O.; Wei, H.; Hwang, G. W.; Montana, D. M.; Coropceanu, I.; Achorn, O. B.; Kloepper, J.; Heeren, J.; So, P. T. C.; Fukumura, D.; Jensen, K. F.; Jain, R. K.; Bawendi, M. G. Nat. Biomed. Eng. 2017, 1 0056.
[99]	Jiang, L.; Wang, K.; Qiu, L. Asian J. Pharm. Sci. 2022, 17 924.
[100]	Yin, B.; Liu, X.; Li, Z.; Ye, Z.; Wang, Y.; Yin, X.; Liu, S.; Song, G.; Huan, S.; Zhang, X.-B. Chin. Chem. Lett. 2024, 110119.
[101]	Sun, B.; Ma, R.; Wang, X.; Ma, S.; Li, W.; Liu, T.; Zhu, W.; Ji, Z.; Hettie, K. S.; Liu, C.; Liang, Y.; Zhu, S. VIEW 2024, 5 20230097.
[102]	Gui, Y.; Chen, K.; Sun, Y.; Tan, Y.; Luo, W.; Zhu, D.; Xiong, Y.; Yan, D.; Wang, D.; Tang, B. Z. Chin. J. Chem. 2023, 41 1249.
[103]	Liu, S.; Li, Y.; Kwok, R. T. K.; Lam, J. W. Y.; Tang, B. Z. Chem. Sci. 2021, 12 3427.
[104]	Xu, W.; Wang, D.; Tang, B. Z. Angew. Chem. Int. Ed. 2021, 60 7476.
[105]	Cheng, Y.; Sun, C.; Ou, X.; Liu, B.; Lou, X.; Xia, F. Chem. Sci. 2017, 8 4571. doi: 10.1039/c7sc00402h pmid: 28626568
[106]	Hu, Z.; Fang, C.; Li, B.; Zhang, Z.; Cao, C.; Cai, M.; Su, S.; Sun, X.; Shi, X.; Li, C.; Zhou, T.; Zhang, Y.; Chi, C.; He, P.; Xia, X.; Chen, Y.; Gambhir, S. S.; Cheng, Z.; Tian, J. Nat. Biomed. Eng. 2020, 4 259.
[107]	Carr, J. A.; Franke, D.; Caram, J. R.; Perkinson, C. F.; Saif, M.; Askoxylakis, V.; Datta, M.; Fukumura, D.; Jain, R. K.; Bawendi, M. G.; Bruns, O. T. Proc. Natl. Acad. Sci. 2018, 115 4465.
[108]	O'Connell, M. J.; Bachilo, S. M.; Huffman, C. B.; Moore, V. C.; Strano, M. S.; Haroz, E. H.; Rialon, K. L.; Boul, P. J.; Noon, W. H.; Kittrell, C.; Ma, J.; Hauge, R. H.; Weisman, R. B.; Smalley, R. E. Science 2002, 297 593. pmid: 12142535
[109]	Zhu, S.; Yang, Q.; Antaris, A. L.; Yue, J.; Ma, Z.; Wang, H.; Huang, W.; Wan, H.; Wang, J.; Diao, S.; Zhang, B.; Li, X.; Zhong, Y.; Yu, K.; Hong, G.; Luo, J.; Liang, Y.; Dai, H. Proc. Natl. Acad. Sci. 2017, 114 962.
[110]	Shi, W.-Q.; Zeng, L.; He, R.-L.; Han, X.-S.; Guan, Z.-J.; Zhou, M.; Wang, Q.-M. Science 2024, 383 326. doi: 10.1126/science.adk6628 pmid: 38236955
[111]	Schmidt, E. L.; Ou, Z.; Ximendes, E.; Cui, H.; Keck, C. H. C.; Jaque, D.; Hong, G. Nat. Rev. Methods Primers 2024, 4 23.
[112]	Zhong, Y.; Ma, Z.; Wang, F.; Wang, X.; Yang, Y.; Liu, Y.; Zhao, X.; Li, J.; Du, H.; Zhang, M.; Cui, Q.; Zhu, S.; Sun, Q.; Wan, H.; Tian, Y.; Liu, Q.; Wang, W.; Garcia, K. C.; Dai, H. Nat. Biotechnol. 2019, 37 1322.
[113]	Naczynski, D. J.; Sun, C.; Türkcan, S.; Jenkins, C.; Koh, A. L.; Ikeda, D.; Pratx, G.; Xing, L. Nano Lett. 2015, 15 96. doi: 10.1021/nl504123r pmid: 25485705
[114]	Cao, X.; Jiang, S.; Jia, M. J.; Gunn, J. R.; Miao, T.; Davis, S. C.; Bruza, P.; Pogue, B. W. J. Biomed. Opt. 2018, 24 1. doi: 10.1117/1.JBO.24.5.051405 pmid: 30468044
[115]	Knez, D.; Hanninen, A. M.; Prince, R. C.; Potma, E. O.; Fishman, D. A. Light Sci. Appl. 2020, 9 125.
[116]	Kim, T.; O'Brien, C.; Choi, H. S.; Jeong, M. Y. Appl. Spectrosc. Rev. 2018, 53 349.
[117]	Wang, F.; Qu, L.; Ren, F.; Baghdasaryan, A.; Jiang, Y.; Hsu, R.; Liang, P.; Li, J.; Zhu, G.; Ma, Z.; Dai, H. Proc. Natl. Acad. Sci. 2022, 119, e2123111119.
[118]	Chen, Y.; Yang, Y.; Zhang, F. Nat. Protoc. 2024, 19 2386.
[119]	Bonis-O'Donnell, J. T. D.; Page, R. H.; Beyene, A. G.; Tindall, E. G.; McFarlane, I. R.; Landry, M. P. Adv. Funct. Mater. 2017, 27 1702112.
[120]	Huisken, J.; Swoger, J.; Del Bene, F.; Wittbrodt, J.; Stelzer, E. H. Science 2004, 305 1007. doi: 10.1126/science.1100035 pmid: 15310904
[121]	Wang, F.; Wan, H.; Ma, Z.; Zhong, Y.; Sun, Q.; Tian, Y.; Qu, L.; Du, H.; Zhang, M.; Li, L.; Ma, H.; Luo, J.; Liang, Y.; Li, W. J.; Hong, G.; Liu, L.; Dai, H. Nat. Methods 2019, 16 545.
[122]	Pei, P.; Chen, Y.; Sun, C.; Fan, Y.; Yang, Y.; Liu, X.; Lu, L.; Zhao, M.; Zhang, H.; Zhao, D.; Liu, X.; Zhang, F. Nat. Nanotechnol. 2021, 16 1011.
[123]	Lu, L.; Li, B.; Ding, S.; Fan, Y.; Wang, S.; Sun, C.; Zhao, M.; Zhao, C.-X.; Zhang, F. Nat. Commun. 2020, 11 4192.
[124]	Zhu, X.; Liu, X.; Zhang, H.; Zhao, M.; Pei, P.; Chen, Y.; Yang, Y.; Lu, L.; Yu, P.; Sun, C.; Ming, J.; Abraham, I. M.; El-Toni, A. M.; Khan, A.; Zhang, F. Angew. Chem. Int. Ed. 2021, 60 23545. doi: 10.1002/anie.202108124 pmid: 34487416
[125]	Yang, Y.; Wang, S.; Lu, L.; Zhang, Q.; Yu, P.; Fan, Y.; Zhang, F. Angew. Chem. Int. Ed. 2020, 59 18380.
[126]	Xu, H.; Yang, Y.; Lu, L.; Yang, Y.; Zhang, Z.; Zhao, C.-X.; Zhang, F.; Fan, Y. Anal. Chem. 2022, 94 3661.
[127]	Cao, C.; Jin, Z.; Shi, X.; Zhang, Z.; Xiao, A.; Yang, J.; Ji, N.; Tian, J.; Hu, Z. IEEE Trans. Biomed. Eng. 2022, 69 2404.
[128]	Qu, Q.; Nie, H.; Hou, S.; Wang, F.; He, K.; Deng, P.; Chen, S.; Zhang, Z.; Chi, C.; Hu, Z.; Shan, H.; Tian, J. Eur. J. Nucl. Med. Mol. Imaging 2022, 49 4752.
[129]	Smith, A. M.; Mancini, M. C.; Nie, S. Nat. Nanotechnol. 2009, 4 710.
[130]	Huang, J.; Su, L.; Xu, C.; Ge, X.; Zhang, R.; Song, J.; Pu, K. Nat. Mater. 2023, 22 1421.

近红外二区荧光探针在活体多重成像中的研究进展

Research Progress on Fluorescent Probes in the Second Near-Infrared Window for In Vivo Multiplexed Imaging

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