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Acta Chimica Sinica >

2012 , Vol. 70 >Issue 05: 635 - 642

DOI: https://doi.org/10.6023/A1105271

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Study on Fingerprint of Crude and Processed Epimedium by UPLC-PDA-MS

  • Zhu Fenxia ,
  • Zhao Yonggang ,
  • Jia Xiaobin ,
  • Wei Yingjie ,
  • Zhang Zhenhai ,
  • Wulazihan Gulinaer
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  • a Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028;
    b Jiangsu Environmental Monitoring Center, Nanjing 210036

Received date: 2011-05-27

  Revised date: 2011-09-05

  Online published: 2011-11-22

Supported by

Project was supported by the National Natural Science Foundation of China (No. 20973944).

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Abstract

The fingerprint chromatograms of E. koreanum Nakai and E. pubescens Maxim were established by UPLC. The results showed that the fingerprints of two species were significantly different. There were 35 common peaks in crude drug of E. koreanum Nakai in which 26 peaks were identified, and 13 common peaks in crude drug of E. pubescens Maxim in which 9 peaks were identified, by MS respectively. Additionally, there were 5 differences in fingerprint between crude drug and processed product. This method with desirable rapidness, simplity and repeatability can be used for the quality evaluation of crude and processed Epimedium.

Key words： Epimedium; UPLC-PDA-MS; processed; fingerprint

Cite this article

Zhu Fenxia , Zhao Yonggang , Jia Xiaobin , Wei Yingjie , Zhang Zhenhai , Wulazihan Gulinaer . Study on Fingerprint of Crude and Processed Epimedium by UPLC-PDA-MS[J]. Acta Chimica Sinica, 2012 , 70(05) : 635 -642 . DOI: 10.6023/A1105271

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