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Acta Chimica Sinica >

2012 , Vol. 70 >Issue 02: 207 - 211

DOI: https://doi.org/10.6023/A1103231

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Study on Syntheses and Anticoagulant Action of Rare Earth Nano-oxides/TDI-CS Hybrid Materials

  • GAO Qi-Kuan ,
  • WANG Kun-Jie ,
  • WANG Xi-Cun
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  • a College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070;
    b College of Petrochemical Technology, Lanzhou University of Technology, Lanzhou 730050;
    c Gansu Health School, Lanzhou 730000

Received date: 2011-03-23

  Revised date: 2011-09-14

  Online published: 2012-02-25

Supported by

Project supported by the National Natural Science Foundation of China (No.21062017) and Natural Science Foundation of Gansu Province (No. 1112RJZA006);Gansu Key Laboratory of Polymer Materials and Lanzhou University of Technology for Ph.D.

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Abstract

Four hybrid materials of RE2O3-TDI-CS (TDI=toluene 2,4-diisocyanate, CS=chitosan, RE=Nd, Eu, La, Sc) were prepared by the method of graft. The materials were characterized by infrared spectroscopy, thermogravimetric and scanning electron microscopy, and results showed that the CS was grafted on the surface of rare earth nano-oxides which was modified by TDI. The results of the experiment of anticoagulant and recalcification time showed that the materials have better anticoagulant action than that of RE2O3.

Key words： chitosan (CS); rare earth nano-oxide; hybrid material; anticoagulant; recalcification

Cite this article

GAO Qi-Kuan , WANG Kun-Jie , WANG Xi-Cun . Study on Syntheses and Anticoagulant Action of Rare Earth Nano-oxides/TDI-CS Hybrid Materials[J]. Acta Chimica Sinica, 2012 , 70(02) : 207 -211 . DOI: 10.6023/A1103231

References

1 Muzzarelli, R. A. Chitin, Pergamon Press, New York, 1997, pp. 1～37.  

2 Roberts, G. F. Chitin Chemistry, Mac Millian Press, Houndmills, 1992, pp. 1～50.  

3 Jiang, Z.-J.; Wang, Z.-Y.; Hu, X.-Q. Chem. Bioeng. 2008, 12, 57 (in Chinese). (蒋珍菊, 王周玉, 胡星琪, 化学与生物工程, 2008, 12, 57.)

4 Funakoshi, T.; Furushima, K.; Shimada, H. Biochem. Int. 1992, 28, 113.

5 Novikova, N. V.; Lobanova, E. G.; Lebedeva, E. N.; Men'kov, A. A.; Galaktionova, O. V. Farmakol. Toksikol. (Moscow) 1986, 49, 32.

6 Wang, K.-J.; Luan, N.-N.; Song, Y.-M. Acta Chim. Sinica 2009, 67, 1042 (in Chinese). (王坤杰, 栾尼娜, 宋玉民, 化学学报, 2009, 67, 1042.)

7 Dong, Y.-L.; Luan, N.-N.; Wang, H.-Y.; Song, Y.-M. Acta Chim. Sinica 2008, 66, 1497 (in Chinese). (董银龙, 栾尼娜, 王海燕, 宋玉民, 化学学报, 2008, 66, 1497.)

8 Song, Y.-M.; Dong, Y.-L.; Fu, Y.-L.; Yao, K.-L. Acta Chim. Sinica 2007, 65, 678 (in Chinese). (宋玉民, 董银龙, 付云龙, 姚卡玲, 化学学报, 2007, 65, 678.)

9 Wang, X.; Lu, L.-D. Chinese J. Inorg. Chem. 2000, 16, 213 (in Chinese). (汪信, 陆路德, 无机化学学报, 2000, 16, 213.)

10 Liu, P.; Chen, Y.-S.; Zhang, L.-H. J. Funct. Polym. 2004, 17, 35 (in Chinese). (刘鹏, 陈亚芍, 张丽惠, 功能高分子学报, 2004, 17, 35.)

11 Shi, H.-T.; Mo, X.-M.; He, C.-L.; Guo, K.; Liu, S.-H. J. Clin. Rehabilitative Tissue Eng. Res. 2008, 12, 10 (in Chinese). (石海涛, 莫秀梅, 何创龙, 过凯, 刘生和, 中国组织工程 研究与临床康复, 2008, 12, 10.)

12 Nag, M.; Basak, P.; Manorama, S. V. Mater. Res. Bull. 2007, 42, 1691.  

13 Watson, S.; Beydoun, D.; Scott, J.; Amal, R. J. Nanopart. Res. 2004, 6, 193.  

14 Li, H. R.; Lin, J.; Zhang, H. J.; Fu, L. S.; Meng, Q. G.; Wang, S. B. Chem. Mater. 2002, 14, 3651.  

15 Lei, X. P.; Su, Z. X. Polym. Adv. Technol. 2007, 18, 472.  

16 Wang, Q.; Ni, J.-Z. Chem. J. Chin. Univ. 2004, 25, 1783 (in Chinese). (王群, 倪嘉缵, 高等学校化学学报, 2004, 25, 1783.)
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