Oxidative Coupling Strategy in the Total Syntheses of Complex Indole Alkaloids
Received date: 2012-12-11
Online published: 2013-01-04
Supported by
Project supported by National Basic Research Program of China (973 program, No. 2010CB833200), the Natural Science Foundation of China (Nos. 21202209, 21132006), the Fundamental Research Funds for the Central Universities (CQDXWL-2012-131), and the Natural Science Foundation Project of CQ CSTC (No. cstc2012jjA10087).
Oxidative coupling as a highly efficient and economic strategy for carbon-carbon bond formation has been applied in the total syntheses of natural products. Recently, Ma’s group achieved the total syntheses of four complex indole alkaloids by developing a highly versatile LiHMDS/I2 oxidative coupling condition, which merits an important progress in this filed. In this highlight, recent progress of Ma’s group is reviewed.
Key words： oxidative coupling; communesin F; communesin A～B; vincorine; total synthesis
Zhang Dan , Qin Yong . Oxidative Coupling Strategy in the Total Syntheses of Complex Indole Alkaloids[J]. Acta Chimica Sinica, 2013 , 71(02) : 147 -150 . DOI: 10.6023/A12121037
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