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About the Cover:On the cover: Direct C—H bond functionalization on pyridines is the most straightforward approach to access pyridine derivatives. In the area of 2-aminocarbonyl pyridine synthesis, the catalysis employing noble metal reagents such as Ag-catalyst, Pd catalyst via the reactions of pyridines with formamides, CO/amine, or isocynanides are the mainstream. In this work, a metal-free tactic is developed by the oxalic acid dihydrate promoted reactions of pyridines and isocyanides via C2-aminocarbonylation reactions, thus providing atom economical and facile access to useful pyridine derivatives. [Liu, Yunyun et al. on page 418-421.]
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