Synthesis of Receptors Based on Pyridio[2,3-d]pyrimidines and Their Anion Recognition

doi:10.6023/cjoc201307040

Chin. J. Org. Chem. ›› 2014, Vol. 34 ›› Issue (2): 382-386.DOI: 10.6023/cjoc201307040 Previous Articles Next Articles

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吡啶并[2,3-d]嘧啶衍生物受体的合成及对阴离子识别研究

黄志斌, 刘学成, 胡明华, 林伟, 史达清

苏州大学材料与化学化工学部江苏省有机合成重点实验室苏州 215123

收稿日期:2013-07-25 修回日期:2013-10-12 发布日期:2013-10-16
通讯作者: 史达清 E-mail:dqshi@suda.edu.cn
基金资助:
江苏省高校自然科学基金（No.11KJB150014）资助项目.

Synthesis of Receptors Based on Pyridio[2,3-d]pyrimidines and Their Anion Recognition

Huang Zhibin, Liu Xuecheng, Hu Minghua, Lin Wei, Shi Daqing

Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123

Received:2013-07-25 Revised:2013-10-12 Published:2013-10-16
Supported by:
Project supported by the Natural Science Fundation of Jiangsu Higher Education Institutions (No. 11KJB150014).

Four new receptors containing pyridio[2,3-d]pyrimidines were synthesized via three-component reaction of 6-aminopyrimidine, substituted benzaldehydes and malononitrile. The properties of the receptors with anions such as F^-, Cl^-, Br^-, AcO^-, HSO₄^- and H₂PO₄^-were examined by UV-Vis spectroscopy. The results showed that receptors have good selectivity to AcO^-. However, no obvious changes were observed on the other anions. The Job plot indicated that a 1:1 stoichiometry complex was formed between receptors and anions. The results also showed that hydrogen-bonding interaction was formed between the receptors and anions. The combination assumed above was confirmed by the results of ¹H NMR titration.

Key words: pyridio[2,3-d]pyrimidines, anion recognition, hydrogen-bonding interaction

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Huang Zhibin, Liu Xuecheng, Hu Minghua, Lin Wei, Shi Daqing. Synthesis of Receptors Based on Pyridio[2,3-d]pyrimidines and Their Anion Recognition[J]. Chin. J. Org. Chem., 2014, 34(2): 382-386.

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吡啶并[2,3-d]嘧啶衍生物受体的合成及对阴离子识别研究

Synthesis of Receptors Based on Pyridio[2,3-d]pyrimidines and Their Anion Recognition

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