Chinese Journal of Organic Chemistry ›› 2017, Vol. 37 ›› Issue (11): 2800-2817.DOI: 10.6023/cjoc201704052 Previous Articles     Next Articles

人工合成类DNA双股高分子的研究进展

朱磊a,b, 李博解a,b, 严沣a, 汪连生a   

  1. a 湖北工程学院化学与材料科学学院 孝感 432000;
    b 生物质资源转化利用湖北省协同创新中心 孝感 432000
  • 收稿日期:2017-04-30 修回日期:2017-07-21 发布日期:2017-08-11
  • 通讯作者: 朱磊, 汪连生 E-mail:lei.zhu@hbeu.edu.cn;wangls@hbeu.edu.cn
  • 基金资助:

    国家自然科学基金(No.21304032)、湖北省自然科学基金(Nos.2016CFB104,2015CFC772)和湖北省教育厅科学技术研究(No.Q20162705)资助项目.

Progress in the Synthesis of DNA-Like Double Strand Polymers

Zhu Leia,b, Li Bojiea,b, Yan Fenga, Wang Lianshenga   

  1. a School of Chemistry and Material Science, Hubei Engineering University, Hubei 432000;
    b HuBei Collaborative Innovation Center for Biomass Conversion and Utilization, Hubei 432000
  • Received:2017-04-30 Revised:2017-07-21 Published:2017-08-11
  • Contact: 10.6023/cjoc201604052 E-mail:lei.zhu@hbeu.edu.cn;wangls@hbeu.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21304032), the Natural Science Foundation of Hubei Province (Nos. 2016CFB104, 2015CFC772), the Hubei Provincial Department of Education Science and Technology Research Projects (No. Q20162705).

Deoxyribonucleic acid (DNA) is the genetic material determining the makeup of all living cells and many viruses. DNA has a self-replicating feature which consists of two polynucleotide chains in the form of a double helix. The synthesis of DNA-like double strand polymers has attracted much attention over recent years due to the development of self-assembly chemistry and organic synthesis technology. The synthesis of double strand polymers divided by the interaction including non-covalent bonding and covalent bonding between linker and backbone is sumarized. Poly-norbornene which could be performed as effcient backbone is also described. A series of isotactic double strand polymeric ladderphanes have been successfully acheived based on such poly-norbornene backbone.

Key words: double strand, polymeric ladderphane, ring opening metathesis polymerization, tacticity