Synthesis and Immobilization of Pyridinium N-Chloramine Precursors on PU Film for Antibacterial Application

doi:10.6023/cjoc201708056

Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (4): 955-962.DOI: 10.6023/cjoc201708056 Previous Articles Next Articles

Notes

吡啶盐-氯胺前体的合成及在聚氨酯表面固载的抗菌应用

李令东, 迟晓芳, 闫佳威, 赵梓含

大连理工大学石油与化学工程学院盘锦 124221

收稿日期:2017-08-27 修回日期:2017-11-28 发布日期:2017-12-08
通讯作者: 李令东 E-mail:lild@dlut.edu.cn
基金资助:
中央高校基本科研业务费（Nos.DUT14RC（3）081，DUT17LK17）和教育部留学回国人员科研启动基金资助项目.

Synthesis and Immobilization of Pyridinium N-Chloramine Precursors on PU Film for Antibacterial Application

Li Lingdong, Chi Xiaofang, Yan Jiawei, Zhao Zihan

School of Petroleum and Chemical Engineering, Dalian University of Technology, Panjin 124221

Received:2017-08-27 Revised:2017-11-28 Published:2017-12-08
Contact: 10.6023/cjoc201708056 E-mail:lild@dlut.edu.cn
Supported by:
Project supported by the Fundamental Research Funds for the Central Universities (Nos. DUT14RC(3)081, DUT17LK17) and the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry.

1. Synthesis and Immobilization of Pyridinium N-Chloramine Precursors on PU Film for Antibacterial Application.PDF(883KB)

Abstract

In this work, two novel pyridinium N-chloramine precursors were designed and synthesized, both of which contain perfluorophenyl azide (PFPA) unit as the photo-coupling handle. The synthetic precursors were photo immobilized on commercial PU films upon UV (254 nm) light irradiation. After exposure to diluted household bleach, the resulting PU films were rendered biocidal. Antibacterial tests showed that satisfactory was achieved for both surface modified films and that the film grafted with shorter alkyl linker-contained precursor demonstrated even higher biocidal efficacy. Non-leaching antibacterial PU materials were herein developed based on PFPA-coupling strategy, providing a simple and universal method to confer N-chloramines on inert polymer surface for antibacterial application.

Key words: pyridinium N-chloramine precursors, multi-step synthesis, fluorophenyl azide (PFPA) chemistry, biocidal polyurethane film, antimicrobial activity

Cite this article

Li Lingdong, Chi Xiaofang, Yan Jiawei, Zhao Zihan. Synthesis and Immobilization of Pyridinium N-Chloramine Precursors on PU Film for Antibacterial Application[J]. Chin. J. Org. Chem., 2018, 38(4): 955-962.

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吡啶盐-氯胺前体的合成及在聚氨酯表面固载的抗菌应用

Synthesis and Immobilization of Pyridinium N-Chloramine Precursors on PU Film for Antibacterial Application

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