Synthesis of Phenoxyallene-Based Amphiphilic Block Copolymer

doi:10.6023/cjoc201710037

Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (12): 3248-3256.DOI: 10.6023/cjoc201710037 Previous Articles Next Articles

Notes

基于苯氧基联烯的两亲性嵌段共聚物的合成

蒋友好^a, 陆国林^b, 彭文^a

a 上海中医药大学附属普陀医院上海 200062;
b 中国科学院上海有机化学研究所上海 200032

收稿日期:2017-10-31 修回日期:2017-11-09 发布日期:2017-11-15
通讯作者: 彭文 E-mail:13061677336@163.com
基金资助:
国家自然科学基金（No.21674124）资助项目.

Synthesis of Phenoxyallene-Based Amphiphilic Block Copolymer

Jiang Youhao^a, Lu Guolin^b, Peng Wen^a

a Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062;
b Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032

Received:2017-10-31 Revised:2017-11-09 Published:2017-11-15
Contact: 10.6023/cjoc201710037 E-mail:13061677336@163.com
Supported by:
Project supported by the National Natural Science Foundation of China (No. 21674124).

An amphiphilic triblock copolymer comprising double-bond-containing poly(phenoxyallene) (PPOA) was synthesized by a combination of conventional free radical polymerization and atom transfer radical polymerization (ATRP) via the site transformation strategy. A new bifunctional initiator containing azo and ATRP initiating groups was prepared and used for conventional free radical homopolymerization of phenoxyallene (POA) to afford a PPOA-based macroinitiator bearing ATRP initiating groups. Subsequent ATRP of hydrophilic monomer, 2-((diethylamino)ethyl methacrylate) (DEAEMA), initiated by PPOA-based macroinitiator afforded PDEAEMA-b-PPOA-b-PDEAEMA triblock copolymer. This triblock copolymer can self-assemble into micelles, and critical micelle concentration (cmc) of PDEAEMA-b-PPOA-b-PDEAEMA amphiphilic triblock copolymer in aqueous solution was determined by ﬂuorescence probe technique. The dependence of cmc on pH and ion strength was also investigated.

Key words: polyallene, block copolymer, bifunctional initiator, ATRP

Cite this article

Jiang Youhao, Lu Guolin, Peng Wen. Synthesis of Phenoxyallene-Based Amphiphilic Block Copolymer[J]. Chin. J. Org. Chem., 2017, 37(12): 3248-3256.

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基于苯氧基联烯的两亲性嵌段共聚物的合成

Synthesis of Phenoxyallene-Based Amphiphilic Block Copolymer

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