Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (7): 2062-2070.DOI: 10.6023/cjoc202003008 Previous Articles     Next Articles


孔庆山a,b, 李兴龙b, 许华建a, 傅尧b   

  1. a 合肥工业大学食品与生物工程学院 合肥 230601;
    b 中国科学技术大学化学系 合肥微尺度物质科学国家实验室 能源材料化学协同创新中心 中国科学院城市污染物转化重点实验室 安徽省生物质洁净能源重点实验室 合肥 230026
  • 收稿日期:2020-03-08 修回日期:2020-04-02 发布日期:2020-04-17
  • 通讯作者: 许华建, 傅尧;
  • 基金资助:

Study on Reaction of γ-Valerolactone and Amine Catalyzed by Zirconium-Based Lewis Acids

Kong Qingshana,b, Li Xinglongb, Xu Huajiana, Fu Yaob   

  1. a School of Food and Biological Engineering, University of Science and Technology of China, Hefei 230601;
    b Hefei National Laboratory for Physical Sciences at the Microscale, Collaborative Innovation Center of Chemistry for Energy Materials, Chinese Academy of Sciences Key Laboratory of Urban Pollutant Conversion, Anhui Province Key Laboratory of Biomass Clean Energy, Department of Chemistry, University of Science and Technology of China, Hefei 230026
  • Received:2020-03-08 Revised:2020-04-02 Published:2020-04-17
  • Supported by:
    Project supported by the National Key Research and Development Program of China (No. 2018YFB1501604), the National Natural Science Foundation of China (No. 21472033), the Key Research and Development Program Projects in Anhui Province (No. 201904a07020069), and the Fundamental Research Funds for the Central Universities.

γ-Valerolactone (GVL) is an important biomass platform molecule, it can be converted into high value-added chemicals and fuel, which has important application prospects. This article describes a method for the synthesis of hydroxyamides and pyrrolidones from GVL and amine compounds by reductive amination/cyclization reactions under mild conditions using zirconium-based Lewis acid catalysts Zr-P-O and ZrOCl2·8H2O, respectively. In particular, a moderately high product yield can be obtained with the absence of a solvent. This method further lays the foundation for the application research of GVL.

Key words: γ-valerolactone, hydroxyamide, pyrrolidone, Lewis acid catalysis, zirconium-based catalyst