Chinese Journal of Organic Chemistry ›› 2023, Vol. 43 ›› Issue (9): 3055-3066.DOI: 10.6023/cjoc202303036 Previous Articles     Next Articles


鄢伯钰a, 吴阶良a, 邓金飞a, 陈丹a, 叶秀深b, 姚秋丽a,b,*()   

  1. a 遵义医科大学药学院 贵州遵义 563000
    b 中国科学院青海盐湖研究所 西宁 810008
  • 收稿日期:2023-03-23 修回日期:2023-05-04 发布日期:2023-06-06
  • 基金资助:
    国家自然科学基金(22161053); 国家自然科学基金(21801261); 贵州省科技厅([2020]1Z003); 贵州省教育厅(20195201900); 遵义医科大学优秀青年人才(18zy-003); 青海省千人计划资助项目

Recent Progress in Light-Driven Direct Dehydroxylation and Derivation of Alcohols

Boyu Yana, Jieliang Wua, Jinfei Denga, Dan Chena, Xiushen Yeb, Qiuli Yaoa,b()   

  1. a College of Pharmacy, Zunyi Medical University, Zunyi, Guizhou 563000
    b Qinghai Institute of Salt Lakes, Chinese Academy of Sciences, Xi'ning 810008
  • Received:2023-03-23 Revised:2023-05-04 Published:2023-06-06
  • Contact: E-mail:
  • Supported by:
    National Natural Science Foundation of China(22161053); National Natural Science Foundation of China(21801261); Guizhou Science and Technology Department([2020]1Z003); Guizhou Education Department(20195201900); Zunyi Medical University Outstanding Young Talents(18zy-003); Thousand Talents Plan of Qinghai Province

Conventional methods for the reduction of alcohols mainly deal with the indirect cleavages of Csp3—O bond involving tedious activated steps. In contrast, the more straightforward direct reduction of naturally abundant aliphatic alcohols to alkanes or other reductive derivatives poses a challenge to organic chemists due to the inherently stable and less reactive Csp3—O bond. The development of direct reductive strategies induced by light is of utmost importance due to their atom economy, step economy and redox economy, and many progresses have been made in this area these years. However, very few reviews on this topic has been reported so far. Herein, the recent progress in the light-driven direct deoxygenation of alcohols with emphasis on important advances last ten years is reviewed, which is expected to further promote the vigorous development of this field.

Key words: alcohols, reduction, alkylation, dehydroxylation, photochemistry