NaNO2 mediated difunctionalizations of alkenes for the synthesis of β-oximino phosphorodithioates

doi:10.6023/cjoc202508016

Chinese Journal of Organic Chemistry

ARTICLE

亚硝酸钠介导烯烃双官能化合成β-肟基二硫代磷酸酯

何卫保^a, 贺梦云^a, 廖琼^a, 易荣楠^*b

^a湖南化工职业技术学院技术与职业教育研究中心株洲 412000
^b湖南警察学院食药环及毒品检验技术湖南省普通高等学校重点实验室长沙 410138

收稿日期:2025-08-17 修回日期:2025-09-24
基金资助:
长沙市自然科学基金(No.104872)资助项目.

NaNO₂ mediated difunctionalizations of alkenes for the synthesis of β-oximino phosphorodithioates

He Weibao^a, He Mengyun^a, Liao Qiong^a, Yi Rongnan^*b

^aResearch Center for Technical and Vocational Education Studies, Hunan Chemical Vocational Technology College, Zhuzhou 412000
^bKey Laboratory of Food & Environment & Drug Monitoring and Testing of Universities in Hunan Province, Hunan Police Academy, Changsha 410138

Received:2025-08-17 Revised:2025-09-24
Contact: *E-mail: yrn@hnu.edu.cn
Supported by:
Foundation of Natural Science Foundation of Changsha (No.104872).

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Abstract

NaNO₂ mediated difunctionalization of alkenes with P₄S₁₀ and alcohols has been developed for the construction of β-oximino phosphorodithioates. This transformation provides an efficient approach to access various β-oximino phosphorodithioates under mild conditions by using NaNO₂ as oxime source. The method features the advantages of simple operation, mild condition, and non metal-pollution. Preliminary mechanistic studies suggest that this reaction occurs through the NO positive ion process.

Key words: sodium nitrite, difunctionalizations of alkenes, P₄S₁₀, β-oximino phosphorodithioates

Cite this article

He Weibao, He Mengyun, Liao Qiong, Yi Rongnan. NaNO₂ mediated difunctionalizations of alkenes for the synthesis of β-oximino phosphorodithioates[J]. Chinese Journal of Organic Chemistry, doi: 10.6023/cjoc202508016.

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亚硝酸钠介导烯烃双官能化合成β-肟基二硫代磷酸酯

NaNO₂ mediated difunctionalizations of alkenes for the synthesis of β-oximino phosphorodithioates

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