Some novel pyridine derivatives derived from 2-(2-pyridyl)propane-1,3-diol

Chin. J. Org. Chem. ›› 1988, Vol. 8 ›› Issue (1): 53-57. Previous Articles Next Articles

从2-(2-吡啶)-1,3-丙二醇衍生出的一些新的吡啶化合物

ALAN R. KATRITZKY;范伟强;李巧玲

佛罗里达大学化学系;杭州大学化学系

发布日期:1988-02-25

Some novel pyridine derivatives derived from 2-(2-pyridyl)propane-1,3-diol

ALAN R. KATRITZKY;FAN WEIQIANG;LI QIAOLING

Published:1988-02-25

Abstract

The title compound (I; R = OH) was treated with SOCl2-pyridine to give 50% dichloropropane I (R = Cl) (II) and 25% oxetane III. Reaction of II with H2NCSNH2 followed by hydrolysis with aqueous NaOH gave 55% allyl mercaptan IV (R1 = SH) and 25% allyl alcohol IV (R1 = OH). Treatment of II with NaCN-DMSO gave 40 and 23% of elimination products IV (R1 = CN, Cl), resp.

Key words: PYRIDINE P, PYRIDINE P, C13 NMR SPECTROMETRY, PROTON MAGNETIC RESONANCE SPECTROMETRY, PROPANEDIOL P, PROPANE P, PROPENE P

CLC Number:

O621

Cite this article

ALAN R. KATRITZKY;FAN WEIQIANG;LI QIAOLING. Some novel pyridine derivatives derived from 2-(2-pyridyl)propane-1,3-diol[J]. Chin. J. Org. Chem., 1988, 8(1): 53-57.

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从2-(2-吡啶)-1,3-丙二醇衍生出的一些新的吡啶化合物

Some novel pyridine derivatives derived from 2-(2-pyridyl)propane-1,3-diol

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