Chin. J. Org. Chem. ›› 1994, Vol. 14 ›› Issue (6): 622-625. Previous Articles     Next Articles

Original Articles

3-取代芳基-2-吲哚基膦酸酯的合成

焦献云;熊发高;陈万义;胡秉方   

  1. 北京医科大学药学院;北京农业大学应用化学研究所
  • 发布日期:1994-12-25

Synthesis of dialkyl-3-substitutedaryl-indolyl- 2-phosphonates

JIAO XIANYUN;CHEN WANYI;HU BINGFANG   

  • Published:1994-12-25

A series of dialkyl-3-substitutedaryl-indolyl-2- phosphonates is prepared according to the general procedure of Fischer indole synthesis. However, when phenylhydrazine hydrochloride is reacted with o, o-diisopropyl-4-chloro- phenylacetyl phosphonate in absolute alcohol O, O diisopropyl-(4'-chlorophenyl)-3H-indolyl-2-phosphonate can be isolated, and its isomerization to the final producte can also be observed.

Key words: PHOSPHONIC ACID ESTER

CLC Number: