Matrix-assisted laser desorption ionization mass spectrometry and its applications in biomacromolecular analysis

Chin. J. Org. Chem. ›› 1997, Vol. 17 ›› Issue (6): 498-506. Previous Articles Next Articles

Original Articles

基质辅助激光解吸离子化质谱及其在生物大分子分析中的应用

吴忆南;陈耀祖;潘远江;沈飙

浙江大学化学系;兰州大学;应用有机国家重点实验室

发布日期:1997-12-25

Matrix-assisted laser desorption ionization mass spectrometry and its applications in biomacromolecular analysis

WU YINAN;CHEN YAOZU;PAN YUANJIANG;SHEN BIAO

Published:1997-12-25

Abstract

In last few years, two important achievements of ionization techniques in mass spectrometry have been developed: matrix- assisted laser desorption ionization (MALDI) and electrospray ionization (ESI). By these innovative techniques, mass spectrometry becomes one of the most important experimental tools for the analysis of biomacromoleculars. In this article, we briefly review the principles, characteristics, sample preparation, matrix selection, instrumentation of MALDI and its current progress in biomacromolecular analysis.

Key words: TIME-OFF FLIGHT MASS SPECTROMETRY, DESORPTION, MASS SPECTROGRAPHY, IONISE (=IONIZE), LASER, BIOMACROMOLECULE, MASS SPECTROGRAPHY

CLC Number:

O621.16

Cite this article

WU YINAN;CHEN YAOZU;PAN YUANJIANG;SHEN BIAO. Matrix-assisted laser desorption ionization mass spectrometry and its applications in biomacromolecular analysis[J]. Chin. J. Org. Chem., 1997, 17(6): 498-506.

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基质辅助激光解吸离子化质谱及其在生物大分子分析中的应用

Matrix-assisted laser desorption ionization mass spectrometry and its applications in biomacromolecular analysis

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