The (R)-N-(β-trichlorogermyl substituted propionyl) thiazolidine-2-thione-4-carboxylic acid ethers [(R)-N-(β -trichlorogermyl substituted propionyl)TTCA ethers] 3a～3d, [α]D^2^0-86.00～-94.35ⅲ and optically active β -trichlorogermyl substituted propionyl chloride 2a～2d were synthesized by the reaction of trichlorogermyl substituted propionyl chloride with (R)-thiazolidine-2-thione-4-carboxylic acid ether [(R)TTCA ethers]. The (R)-N-(substituted propionyll thiazolidine-2-thione-4-alkyloxycarbonyl) germanium sesquioxides 4a～4d, [α]D^2^0-44.48～-77.00ⅲ were obtained by the hydrolysis of compounds 3a～3d. The electronic structure of reactants and products have been studied by quantum chemisty MNDO method. Reactive enthalpy ΔH have been obtained.

Key words: INFRARED SPECTROPHOTOMETRY, ELEMENTAL ANALYSIS, CARBOXYLIC ACID ESTER, ELECTRONIC STRUCTURE, ACYL CHLORIDES P, ORGANO GERMANIUM, THIAZOLE P