Chin. J. Org. Chem. ›› 1999, Vol. 19 ›› Issue (2): 200-203. Previous Articles    

Original Articles

一步法合成取代-1, 2-苯醌类化合物

张小春;黄志纾;魏海枫;王植材;马林;古练权   

  1. 中山大学化学系.广州(510275)
  • 发布日期:1999-04-25

One-pot preparation of 4, 5-disubstituted-1, 2-benzoquinones

Zhang Xiaochun;Huang Zhishu;Wei Haifeng;Wang Zhicai;Ma Lin;Gu Lianquan   

  1. Zhongshan Univ., Dept Chem.Guangzhou(510275)
  • Published:1999-04-25

In the presence of the immobilized polyphenol oxidase, a one-pot preparation of 4, 5-disubstituted-1, 2-benzoquinones, such as 4, 5-di- aniline-1, 2-benzoquinone, 4, 5-di-(p-methyl aniline)-1, 2- benzoquinone, 4, 5-di-(m-chloroaniline)-1, 2-benzoquinone and 4, 5-di- (p-bromoaniline)-1, 2-benzoquinone, was achieved successfully by using the oxidation-Michael addition. The same results were obtained using I~2-KI instead of the immobilized polyphenol oxidase. The proposed oxidation (Michael addition mechanism has been demonstrated by UV-Vis spectroscopy.

Key words: MICHAEL ADDITION REACTION, BENZOQUINONE P, ELEMENTAL ANALYSIS, ULTRAVIOLET SPECTROPHOTOMETRY, PROTON MAGNETIC RESONANCE SPECTROMETRY, POLYPHENOLOXIDASE, MASS SPECTROGRAPHY

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