Synthesis of imidazole-cobyrinate and studies of  stability of Co-N bond

Chin. J. Org. Chem. ›› 1999, Vol. 19 ›› Issue (5): 523-527. Previous Articles Next Articles

Original Articles

咪唑钴啉酯的合成及钴-氮键稳定性的研究

冯亚青;张卫红;闫喜龙;李熙风

天津大学化工学院应用化学与精细化工系

发布日期:1999-10-25

Synthesis of imidazole-cobyrinate and studies of stability of Co-N bond

Feng Yaqing;Zhang Weihong;Yan Xilong;Li Xifeng

Published:1999-10-25

Abstract

VB~1~2 model molecule, cyano-N-methyl-3-imidazolyl cobyrinate perchlorat 8 was synthesized from the vitamin B~1~2. 8 was treated with acidic buffers in methanol to give compounds 9 and 10. UV-Vis spectra were determined in buffers of different pH values and equilibrium constants of Co-N bonds were calculated. The strength of coordination valence between the central Co atom of cobyrin ring with the N atom of isolated N-methylimidazole ligand is weaker than that of ligand linked with cobyrin cycle.

Key words: MODEL COMPOUND, VITAMIN B12, EQUILIBRIUM CONSTANT, IMIDAZOLE P

CLC Number:

O627

Cite this article

Feng Yaqing;Zhang Weihong;Yan Xilong;Li Xifeng. Synthesis of imidazole-cobyrinate and studies of stability of Co-N bond[J]. Chin. J. Org. Chem., 1999, 19(5): 523-527.

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咪唑钴啉酯的合成及钴-氮键稳定性的研究

Synthesis of imidazole-cobyrinate and studies of stability of Co-N bond

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