Synthesis of some substituted 3-(3'-acetyl-5'-aryl-1',3',4'-oxadiazoline-2'-yl)-chromones

Chin. J. Org. Chem. ›› 2000, Vol. 20 ›› Issue (1): 72-80. Previous Articles Next Articles

3-(2-噁二唑啉基)-色酮类化合物的合成研究

于建新;刘方明;鲁文杰;李燕萍;糟新民;刘育亭;刘丛

新疆大学化学系.新疆(830046);新疆师范大学化学系.乌鲁木齐(830002)

发布日期:2000-02-25

Synthesis of some substituted 3-(3'-acetyl-5'-aryl-1',3',4'-oxadiazoline-2'-yl)-chromones

Yu Jianxin;Liu Fangming;Lu Wenjie;Li Yanping;Zao Xinmin;Liu Yuting;Liu Cong

Xinjiang Univ, Dept Chem.Xinjiang(830046);Xinjiang Normal Univ., Dept Chem.Wulumuqi(830002)

Published:2000-02-25

Abstract

By the Vilsmeier-Haack reaction, chromone-3-carboxaldehydes (2a ～2e) swere prepared in high yields, whichreacted regiospecifically with substituted aroyl hydrazines (3a～3c) in EtOH containing AcOH at room temperature to give 3-(substituted aroly hydrazone)chromones (4a～4o). 4a～4o could be readily converted to substituted 3-(3-acetyl-5-aryl-1,3,4-oxadiazoline-2(-yl)-chromones (5a～5o) in good yields by refluxing with Ac2O. Their structures were established by elemental analysis, IR, ^1H NMR and MS spectra.

Key words: CHROMONE P, HYDRAZIDE P, ACETOPHENONE P, INFRARED SPECTROPHOTOMETRY, PROTON MAGNETIC RESONANCE SPECTROMETRY, MASS SPECTROGRAPHY

CLC Number:

O621

Cite this article

Yu Jianxin;Liu Fangming;Lu Wenjie;Li Yanping;Zao Xinmin;Liu Yuting;Liu Cong. Synthesis of some substituted 3-(3'-acetyl-5'-aryl-1',3',4'-oxadiazoline-2'-yl)-chromones[J]. Chin. J. Org. Chem., 2000, 20(1): 72-80.

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3-(2-噁二唑啉基)-色酮类化合物的合成研究

Synthesis of some substituted 3-(3'-acetyl-5'-aryl-1',3',4'-oxadiazoline-2'-yl)-chromones

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