With the acid of polarizability effect index (PEI) of alkyl group, equilibrium electronegativity of affinity atom in molecules (XE) and Pauling electronegativity of affinity atom (X) the common rule of gas phase basicity (PA) for aliphatic amines, alcohols, ethers has been investigated. The results indicate that PA of aliphatic amines, alcohols, ethers can quantitatively be described as follows: PA (KJ/mol)=2468.6730+557.3172∑ PEI-551.4261 XE-1230.5770 (∑ PEI/XE)- 111.5537 X Based on this relation, the gas phase basicities of 64 aliphatic amines, alcohols, ethers are predicted with average absolute relative error ≤ 0.34%.

Key words: ALIPHATIC AMINES, ALIPHATIC ALCOHOLS, GAS PHASE, ALKALINITY