1-Ethynyl-l-cyeloheptanol reacted with tribenzylstannyl hydride ( C- 6H-5CH-2 )sSnH generating the corresponding (Z)-l-[2-(tribenzylstannyl) vinyl]-1-cycloheptanol (1) . The compound 1 obtained reacted with one or two equivalents of halogen (I-2, Br-2 or IC1) to form the associated ( Z)-l-[2-( dibenzylhalostannyl) vinyl ]-l-cycloheptanol or ( Z)-l-[2 ( benzyldihalostannyl) vinyl]-1-cycloheptanol (2-7), respectively. The organotin hydroxide 8 was prepared by the reaction of 3 with KOH. All compounds were characterized by elemental analysis, IR and H NMR spectra, and the antitumor activity of compounds 1, 3, 4, 6 and 7 was determined. And it was found that they were potent antitumor agents, being effective against P388 cells in mice.

Key words: ORGANO TIN COMPOUNDS;HEPTANOL P;ANTICARCINOGEN;ADDITION REACTION, ELEMENTAL ANALYSIS;IR;1HNMR;STRUCTURE CHARACTERISTICS