Study on the Nucleophilic Substitutions of 4,4'-Difluorobenzil with Amines

Chin. J. Org. Chem. ›› 2003, Vol. 23 ›› Issue (8): 861-864. Previous Articles Next Articles

胺类化合物与4，4’-二氟苯偶酰的亲核取代反应研究

阮继武;黄忠京;符立梧;马林;古练权

中山大学化学与化学工程学院;广西民族学院化学化工系;中山大学肿瘤防治中心

发布日期:2003-08-25

Study on the Nucleophilic Substitutions of 4,4'-Difluorobenzil with Amines

Ruan Jiwu;Huang Zhongjing;Fu Liwu;Ma Lin;Gu Lianquan

School of Chemistry and Chemical Engineering, Zhongshan University;Department of Chemistry and Chemical Engineering, Guangxi Institute for Nationalities;Cancer Center, Zhongshan University

Published:2003-08-25

Abstract

Some symmetric and asymmetric 4,4'-bis(dialkylamino)benzils have been synthesized through the nudeophilic substitutions of 4, 4'-difLuorobenzil with amines. Their structures have been characterized by EA, IR, :H NMR and MS spectra. When primary amines were employed for the reaction, both the substitution and condensation occured in the substrate molecule. The mechanism of this reaction was discussed as well.

Key words: amine;difluorobenzil;NUCLEOPHILIC REACTION;SUBSTITUTION REACTION, REACTION MECHANISM;ELEMENTAL ANALYSIS;IR;1HNMR;MS

CLC Number:

O621

Cite this article

Ruan Jiwu;Huang Zhongjing;Fu Liwu;Ma Lin;Gu Lianquan. Study on the Nucleophilic Substitutions of 4,4'-Difluorobenzil with Amines[J]. Chin. J. Org. Chem., 2003, 23(8): 861-864.

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胺类化合物与4，4’-二氟苯偶酰的亲核取代反应研究

Study on the Nucleophilic Substitutions of 4,4'-Difluorobenzil with Amines

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