Chinese Journal of Organic Chemistry ›› 2004, Vol. 24 ›› Issue (4): 440-443. Previous Articles     Next Articles

3-甲基犬尿喹啉酸衍生物的合成

张梅, 杨凤志, 邹新琢*   

  1. 华东师范大学化学系 上海 200062
  • 收稿日期:2003-06-17 修回日期:2003-09-08 接受日期:2003-10-17 发布日期:2022-09-19

Synthesis of 3-Methylkynurenic Acid Derivatives

ZHANG, Mei, YANG, Feng-Zhi, ZOU, Xin-Zhuo*   

  1. Department of Chemistry, East China Normal University, Shanghai 200062
  • Received:2003-06-17 Revised:2003-09-08 Accepted:2003-10-17 Published:2022-09-19
  • Contact: *E-mail: xzzou@chem.ecnu.edu.cn

Six derivatives of 3-methylquinoline acids having latency biological activity were synthesized by addition of substituted anilinesto ethyl ethoxalylpropionate and followed by high-temperature cyclization. Among them, three new compounds containing fluorine were identified through elemental analyses, 1H NMR, IR and MS spectra.

Key words: substituted aniline, 3-methylquinoline acid, compounds containing fluorine