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Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (11): 1406-1409. Previous Articles Next Articles
Original Articles
胡晓芬,冯亚青*,苏琦
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HU Xiao-Fen,FENG Ya-Qing*,SU Qi
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Two types of cycloalkeno[1,2-d]pyrimidin-2-thiones (2) reacted with chloroacetic acid and the appropriate aldehyde to give 5-aryl-2,8-bis(arylmethylene)-2,3,6,7-tetrahydro-5H,8H-cyclopenta[1,2-d]thi- azolo[3,2-a]pyrimidin-3-ones (3) and 5-aryl-2,10-bis(arylmethylene)-2,3,6,7,8,9-hexahydro-5H,10H-cyclo- hepta[1,2-d]thiazolo[3,2-a]pyrimidin-3-ones (4) respectively, which show potential anticancer activities. Structures of novel compounds 3 and 4 were determined by 1H NMR, IR and MS spectra.
Key words: cycloalkeno[1,2-d]thiazolo[3,2-a]pyrimidin-3-one, fused heterocyclic, synthesis, deter
HU Xiao-Fen,FENG Ya-Qing*,SU Qi. Synthesis of Novel Cycloal-keno[1,2-d]thiazolo[3,2-a]pyrimidin-3-ones[J]. Chin. J. Org. Chem., 2005, 25(11): 1406-1409.
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