Microwave Promoted Synthesis and Biology Activity of 2-Aryloxymethylbenzimidazole-1-acetic Acid Derivatives

Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (9): 1116-1120. Previous Articles Next Articles

Original Articles

微波促进下2-芳氧甲基苯并咪唑-1-乙酸衍生物的合成及生物活性研究

魏太保，师海雄，张治仁，崔文辉，张有明*

(西北师范大学化学化工学院甘肃省高分子材料重点实验室兰州 730070)

收稿日期:2006-12-11 修回日期:2007-03-20 发布日期:2007-08-30
通讯作者: 张有明

Microwave Promoted Synthesis and Biology Activity of 2-Aryloxymethylbenzimidazole-1-acetic Acid Derivatives

WEI Tai-Bao,SHI Hai-Xiong,ZHANG Zhi-Ren
CUI Wen-Hui,ZHANG You-Ming*

(College of Chemistry and Chemical Engineering, Gansu Key Laboratory of Polymer Materi-als,
Northwest Normal University, Lanzhou 730070)

Received:2006-12-11 Revised:2007-03-20 Published:2007-08-30
Contact: ZHANG You-Ming

Abstract

Ten novel derivatives of 2-aryloxymethylbenzimidazole-1-acetic acid were synthesized by N-alkylation of 2-aryloxymethylbenzimidazoles with methyl chloroacetate under MWI and PTC conditions using PEG-400 as a phase transfer catalyst in the presence of potassium carbonate. All the products were characterized by elemental analysis, FT-IR, ¹H NMR and ¹³C NMR spectra. The preliminary biological activity tests show that all the compounds have obvious regulating activities for the growth of the wheat.

Key words: biology activity, phase transfer catalysis, 2-aryloxymethylbenzimidazole-1-acetic acid, microwave promoted synthesis

Cite this article

WEI Tai-Bao,SHI Hai-Xiong,ZHANG Zhi-Ren
CUI Wen-Hui,ZHANG You-Ming*. Microwave Promoted Synthesis and Biology Activity of 2-Aryloxymethylbenzimidazole-1-acetic Acid Derivatives[J]. Chin. J. Org. Chem., 2007, 27(9): 1116-1120.

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微波促进下2-芳氧甲基苯并咪唑-1-乙酸衍生物的合成及生物活性研究

Microwave Promoted Synthesis and Biology Activity of 2-Aryloxymethylbenzimidazole-1-acetic Acid Derivatives

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